This retrospective study aimed to evaluate the clinical course of COVID-19, alterations in maternal steroid hormone levels, and associated perinatal outcomes in pregnant women infected with SARS-CoV-2 during the third trimester. A total of 100 pregnant women were enrolled, including 100 patients with confirmed COVID-19. The findings demonstrated that even mild forms of the infection were associated with increased maternal risks, whereas severe disease was accompanied by a significant decline in estradiol and progesterone concentrations, indicating impaired uteroplacental blood flow. The most frequent obstetric complications included iron-deficiency anemia (37.5%), threatened preterm birth (27.5%), and a high cesarean section rate (47.5%). Neonatal resuscitation was required in 7.5% of cases. Overall, the study confirms that COVID-19 substantially increases the risk of adverse clinical and perinatal outcomes in late pregnancy.

The COVID-19 pandemic poses a significant health risk for pregnant women. Due to physiological immunosuppression during pregnancy, the risk of severe COVID-19 and complications in pregnant women is higher. Thus, studying the safety and efficacy of COVID-19 vaccination during pregnancy is a pressing issue.

As a result of pandemics and advances in the field, the use of telemedicine has grown rapidly due to COVID-19, especially in large, industrialized countries such as the UK, USA and . China. The lack of effective treatment and the large proportion of individuals still unvaccinated, social distancing and lockdown measures suggest that telemedicine is a safe method of patient-physician interaction. In this article, we reviewed the literature on the use of telemedicine during the COVID-19 pandemic.

The article is devoted to the actual problem of modern dentistry: the clinical course and diagnosis of trophic ulcers of the oral mucosa in post-COVID patients. According to various authors, in patients who have undergone COVID-19, there are numerous complications in the oral cavity in the form of hemorrhagic manifestations, angular cheilitis, candidiasis, pigmentation, and trophic ulcers (Khabadze Z.S., et al., 2020). The task of the dentist is to timely diagnose dental manifestations in patients who have had a coronavirus infection and choose the most adapted algorithm for their treatment, depending on the clinical manifestations in the oral cavity.

The study of the condition of the skin and its appendages in patients after Covid-19 infection is today considered one of the pressing problems in modern medicine. Hair loss in this case occurs most often, including purulent alopecia. Our study involved 84 patients with alopecia areata that occurred as a result of COVID-19 infection. Patients were monitored for 6 months from the date of onset of the underlying disease.

Rheumatoid arthritis is the most common inflammatory disease of the joints, characterized by erosive symmetrical polyarthritis in combination with systemic immune-inflammatory damage to internal organs. One of the most severe and widespread inflammatory diseases of the joints. Rheumatoid arthritis is a common disease, occurring in all countries in approximately 1% of the total population. New data have shown that respiratory viral infections may increase the risk of autoimmune inflammatory arthritis, such as rheumatoid arthritis. In addition, infections may worsen the disease in patients with inflammatory arthritis.

COVID-2019 coronavirus-associated disease is an infectious disease caused by a new, previously unknown coronavirus. Most COVID-19 patients present with mild to moderate symptoms and recover without specific treatment.

In this article, the epidemiology of diseases of the digestive system of covid-19 assoculated food was to determine the importance and place of computed tomography in patients with COVID-19. The purpose of the study is devoted to the study of the speed and characteristics of the occurrence of X-ray manifestations of coronavirus infection, lung injuries in companion diseases. To this end, clinical examples were given from patients with COVID-19 during the study.

He found that the predictive danger of a difficult disease in treating COVID-19 is complex, serious illness, and death. Metabolic disorders associated with cardiovascular disease, chronic respiratory diseases and obesity, including the passage of insulin sensitivity, chronic inflammation, lipid and fatty acids, increase the immunological dysregness of the exchange of exchange of metabolism, and the greater tendency of infectious diseases of such patients. Study studies provide the blood of studying the effects of regular taking of drugs prescribed for cardiovascular and other treatment treatments on a patient on the severity and outcomes of COVID-19. Sharing agileness with patients walking under the condition of a renewed causative agent of COVID-19.

The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has significantly impacted medical practices globally, particularly in the management of pregnant women. Due to physiological and immunological changes, pregnant women are at a higher risk of severe COVID-19 complications, which can negatively affect both the mother and fetus. This article aims to analyze studies on COVID-19's impact on pregnancy during different gestational stages and propose preventive measures tailored to each trimester. The review includes data from studies in various countries, covering risks such as miscarriage, preeclampsia, preterm birth, and placental blood flow impairment across trimesters. Social factors like access to healthcare, psychological impacts, and long-term health consequences for both mother and child are also discussed. The findings emphasize the importance of preventive protocols and the need for further research on pregnancy management during the COVID-19 pandemic to enhance maternal and fetal outcomes.

COVID-19 pandemiyasi butun dunyo bo‘ylab sog‘liqni saqlash tizimlariga, ayniqsa, akusherlik va ginekologiya sohalariga jiddiy ta’sir ko‘rsatdi. SARS-CoV-2 bilan infeksiyalangan homilador ayollar gestatsiya davriga qarab o‘zgaruvchi asoratlar xavfiga duch keladi. Ushbu tadqiqotning maqsadi COVID-19ning homiladorlikning turli gestatsion davrlariga ta’sirini tahlil qilish va har bir trimestga mos profilaktika choralarini taklif etishdan iborat. 2020–2023-yillarda COVID-19 bilan infeksiyalangan homilador ayollarning tibbiy ma’lumotlari retrospektiv tahlil qilindi. Natijalar homiladorlikning har bir trimestrida turli asoratlar xavfini aniqlab, trimestga xos profilaktika choralarini ishlab chiqish zarurligini tasdiqlaydi. Birinchi trimestrda homiladorlikni to‘xtatish va yallig‘lanish jarayonlari asosiy xavflar hisoblanadi, ikkinchi trimestrda preeklampsiya va gestatsion gipertenziya xavfi yuqori. Uchinchi trimestrda esa og‘ir respirator asoratlar va muddatidan oldin tug‘ruq xavfi yuqori bo‘ladi. Ushbu tadqiqot natijalari COVID-19 bilan bog‘liq asoratlarning oldini olish va davolash uchun maxsus tibbiy protokollarni takomillashtirish uchun muhim manba hisoblanadi.

Most endocrine diseases are chronic, with up to 80% of cases occurring in patients with endocrinopathies, primarily diabetes mellitus and thyroid diseases, who receive regular outpatient care. For such people, an endocrinologist is most often also a general practitioner, so it is their responsibility to promptly explain to patients with diabetes, thyroid, pituitary and adrenal diseases, and endocrine tumors how to behave in the new conditions of the coronavirus disease (COVID-19) pandemic. This infectious disease is most severe in people over 65 years of age with chronic diseases, especially endocrinopathies. This literature review summarizes the current information on the pathogenesis and course of COVID-19, including in the most vulnerable groups. The article provides up-to-date information on measures to prevent infection, the specifics of patient-doctor contact in conditions of self-isolation and quarantine measures, as well as what additional treatment measures are necessary in the development of COVID-19 in patients with the most severe endocrinopathies.

Одной из наиболее острых медико-социальных проблем современного общества уже в течение 2 лет является новая коронавирусная инфекция – CоronaVirus Disease 2019 (COVID-19) – и поиски путей адекватного ведения пациентов с данным заболеванием и его осложнениями. Тяжелое течение COVID-19 повышает риск развития неврологических симптомов и осложнений. Поражение головного мозга при COVID-19 может оказывать долгосрочное влияние на когнитивные процессы. Сосудистые и  когнитивные нарушения представляют важную медико-социальную проблему [4,10].

Corona-virus disease 2019 (COVID-19) first occurred in Wuhan, China, in December 2019. As of April 15, 2020, more than 1.9 million COVID-19 cases had been confirmed worldwide, with over 120,000 deaths. To more effectively prevent COVID-19 proliferation, there is a pressing need to monitor and guess COVID-19 incidence. Time series models help anticipate the impact of the COVID-19 epidemic and determine how to respond to this catastrophe.

COVID-19 — это новое появившееся инфекционное заболевание человека, ознаменовавшее начало третьего десятилетия XXI века. Новый коронавирус, вызывающий COVID-19, получил обозначение «коронавирус тяжелого острого респираторного синдрома 2» (SARS-CoV-2) [21]. Впервые о нем сообщили в городе Ухань, Китай, и он быстро распространился по стране, вызвав эпидемию. COVID-19 затронул почти все страны мира и был зарегистрирован среди людей всех возрастов, включая детей [27]. 11 марта 2020 года ВОЗ объявила COVID-19 пандемией, которая позже была описана ВОЗ 23 марта как «ускоряющаяся пандемия», когда количество случаев заболевания превысило 350 000 [24].

Rheumatoid arthritis (RA) is a rheumatological disease accompanied by joint syndrome, functionally characterized by erosive damage and destruction of joints. The disease occurs predominantly in young and middle-aged individuals and leads to early disability of patients, which in turn determines the social significance and relevance of the problem. COVID-19 infection has caused new features of the course of RA, which determines the medical and social relevance of studying the problem.

В этой статье исследуются макроскопические изменения, наблюдаемые в тонком кишечнике в период после COVID-19. По мере того, как пандемия COVID-19 продолжает развиваться, становится все более очевидным, что вирус может оказывать значительное воздействие на различные органы, включая желудочно-кишечную систему. Недавние исследования показали, что тонкая кишка, важнейший компонент пищеварительного тракта, может претерпевать заметные структурные и функциональные изменения после заражения COVID-19. В этом обзоре рассматриваются клинические наблюдения и результаты исследований, связанные с изменениями в тонком кишечнике после COVID, подчеркивая потенциальные последствия для долгосрочного здоровья и клинического ведения.

Koronavirus infeksiyasi o’tkir respirator kasallik bo’lib, u yuqori nafas yo’llarinng yallig’lanishi va sust namoyon bo’ladigan umumiy zaharlanish belgilari bilan kechadigan kasallikdir. Hozirgi vaqtda COVID-19 infeksiyasining klinik ko'rinishlari va perinatal natijalari bo'yicha cheklangan ma'lumotlar mavjud. COVID-19 ayniqsa homilador ayollar uchun xavf omilidir.

As we know, on March 11, 2020, the World Health Organization declared a pandemic of SARS-CoV-2 (COVID-19) coronavirus, and from that day, a new coronavirus pandemic started in all countries.  It is a new type of disease whose development, course, clinic and treatment are not yet fully understood, making it difficult to control the disease.  A total of 54,482,449 cases and 1,318,612 deaths have been diagnosed, according to data released Nov. 16 by Johnson Hopkins University in the United States.  Pregnant women account for 2-5% of cases and the mortality rate is as high as 25% (SSV Russia, May 2020).  The highest risk group of pregnant women with COVID-19 billion are additional somatic diseases: cardiovascular diseases, arterial hypertension, chronic lung diseases, bronchial asthma of moderate and severe degree, diabetes mellitus, cancer, obesity (TVI>40), kidney disease, liver disease, AFS.  This review explores the modes of action and resistance mechanisms of widely used antimicrobials, as well as the current state of AMR in the most critical resistant bacteria identified by the WHO’s global priority pathogens list.

2019-yilda aniqlangan yangi koronavirus kasalligi 3 yildan buyon vaqt davomida butun dunyo bo'ylab tarqalib, bu infeksiyasiyaning  yuqish va o'lim xavfi yuqoriligicha qolmoqda. COVID-19 bilan kasallanganlarda turli organlar va tizimlarga ta'sir qiladigan, dastlabki tiklanishdan keyin bir necha haftadan bir necha oygacha davom etadigan turli oqibatlar va asoratlar rivojlanishi mumkin. COVID-19 dan tuzalgan odamlarda turli oqibatlar va asoratlar nafaqat kattalar va qarilarda, balki yoshlarda ham paydo bo'lishi mumkin. COVID-19 kasalligining o'tkir davrida ham, bemorlarning qisqa va uzoq muddatli kuzatuv davrida ham bemorlarda individual nevrologik simptomlar, sindromlar kuzatiladi.

Статья посвящена обзору данных о распространенности и влиянии сердечно-сосудистых заболеваний на течение и исходы новой коронавирусной инфекции COVID-19. В обзоре разбирается связь между COVID-19 и функционированием ренин-ангиотензин-альдостероновой системы, патофизиологические механизмы их взаимного влияния. Приведены результаты анализа последних данных литературы о безопасности приема ингибиторов ангиотензинпревращающего фермента и блокаторов рецепторов к ангиотензину II.

COVID-19 pandemiyasi virusning asosan nafas yo‘llariga ta’siri orqali tanilgan bo‘lsa-da, yurak-qon tomir tizimi ham virus va uni keltirib chiqaradigan immun–vaskulyar stresslar orqali sezilarli zarar ko‘rishi mumkin. Ushbu maqolada COVID-19 infektsiyasining yurak va qon tomirlarga bo‘lgan ta’siri, ya’ni miyokardiy ziyon, aritmiyalar, trombotik hodisalar va qon tomir disfunktsiyasi kabi holatlar, shuningdek, “uzoq COVID” davrida paydo bo‘ladigan yurak-qon tomir kasalliklari xavfi tahlil qilinadi. Tahlil natijalari asosida klinik monitoring va davolash bo‘yicha takliflar keltiriladi.

Мақолада  анамнезида қалқонсимон без касаллиги бор ва қалқонсимон без касаллиги йўқ беморларда  COVID-19 инфекциясининг қалқонсимон без тўқимасига УТТ ва гистология натижалари орқали бахоланганлиги ўрганилган. Олинган натижаларга кўра  COVID-19 инфекцияси билан касалланган анамнезида қалқонсимон без касаллиги бўлган 200 та беморда қалқонсимон без хажми катталашганлиги , қалқонсимон  без касаллиги бўлмаган беморларга нисбатан  III-даражада катталашган буқоқлар 34%га, IV-даражада катталашган буқоқлар эса 2%га кўпайганлиги аниқланди. Қалқонсимон без тўқимасида аниқланган касалликлар тахлил қилинганда  1-гурухдаги анамнезида қалқонсимон без касалликлари бўлган беморларда COVID-19 инфекциясидан кейин кўп тугунли буқоқ шакллари аниқланди ва гистология текширув натижаларида қалқонсимон без саратони касаллиги тасдиқланди.

Одной из наиболее острых медико-социальных проблем современного общества уже в течение 2 лет является новая коронавирусная инфекция – CоronaVirus Disease 2019 (COVID-19) – и поиски путей адекватного ведения пациентов с данным заболеванием и его осложнениями. Тяжелое течение COVID-19 повышает риск развития неврологических симптомов и осложнений. Поражение головного мозга при COVID-19 может оказывать долгосрочное влияние на когнитивные процессы. Сосудистые и  когнитивные нарушения представляют важную медико-социальную проблему [2,3].

Ушбу ишда илгари COVID-19 ўтказган беморларда клиник-лаборатор усуллар асосида оғиз бўшлиғи шиллиқ қавати касалликларининг ташхисоти ўтказилди. COVID-19 ўтказган беморларда оғиз бўшлиғини текшириш натижасида турли хил стоматологик симптомлар аниқланди. COVID-19 билан касалланган беморларни текшириш натижасида олинган маълумотлар беморларнинг ушбу тоифасида улар клиник соғайганларидан кейин стоматологик текширувни киритиш зарурлигини ва мақсадга мувофиқлигини тасдиқлайди.