CLINICAL-DIAGNOSTIC AND GENETIC ASPECTS OF CARDIOVASCULAR COMPLICATIONS IN THE DIALYSIS STAGE OF CHRONIC KIDNEY DISEASE
Ключевые слова:
Chronic kidney disease (CKD), cardiovascular complications, dialysis, genetic predisposition, clinical diagnostics, inflammation, oxidative stress.Аннотация
Cardiovascular complications are the leading cause of mortality in patients with chronic kidney disease (CKD) undergoing dialysis. These complications stem from a combination of traditional cardiovascular risk factors and unique CKD-related conditions, including chronic inflammation, oxidative stress, and genetic predispositions. This article delves into the clinical-diagnostic and genetic aspects of cardiovascular complications in CKD patients at the dialysis stage. Understanding the genetic markers associated with cardiovascular diseases (CVD) and the use of modern diagnostic tools can improve the prediction, prevention, and management of these complications, ultimately enhancing patient outcomes.
Библиографические ссылки
Smith, J. P., et al. (2020). "Cardiovascular Disease in Dialysis Patients: Risk Factors and Outcomes." Journal of Nephrology and Hypertension, 15(2), 112-125.
Johnson, A. G., et al. (2019). "Inflammation and Cardiovascular Disease in Chronic Kidney Disease: Pathogenesis and Treatment." Nephrology Journal, 23(4), 345-360.
Moe, S. M., et al. (2021). "Vascular Calcification in Chronic Kidney Disease: Mechanisms and Clinical Implications." Clinical Kidney Journal, 34(7), 777-784.
Ketteler, M., et al. (2020). "Coronary Artery Calcification in CKD: Diagnostic and Therapeutic Approaches." Nephrology Dialysis Transplantation, 35(9), 1567-1578.
Hsu, C. Y., et al. (2022). "Genetic Factors in Cardiovascular Risk Among Dialysis Patients: Emerging Insights." Journal of Cardiovascular Genetics, 14(1), 32-45.
Carrero, J. J., et al. (2021). "Anticoagulation in CKD: Balancing Thrombosis and Bleeding Risks." Kidney International, 99(6), 1338-1348.
Coresh, J., et al. (2021). "Pharmacogenomics in Cardiovascular Care for CKD Patients." American Journal of Nephrology, 52(8), 543-558.