CREATION OF A NEW MODEL OF BURNS IN RATS WITH THE DETERMINATION OF THEIR DEGREE AND THE USE OF CARBOXYMETHYLCHITOSAN APIS MELLIFERA
Keywords:
chitosan, carboxymethylchitosan, modeling, burn injury, epithelialization.Abstract
The article provides information about thermal skin burns and emerging pathophysiological changes in integumentary tissues. The aim of studying and treat these severe processes, burn the skin of animals. A new model of thermal skin injury in rats has been created. For the occurrence of a skin burn, a soldering gun with a flat rod PP REXANT ZD-715 12-0188 with a tip heating temperature of up to 400 0C was used. The degree of the burn was determined by histological examination of skin tissues under a microscope, which was grade IIIA and IIIB. Positive results of using an ointment based on carboxymethylchitosan (CMHZ) have been recorded.
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