THE ROLE OF MYOCARDIAL HYPERTROPHY AND VENTRICULAR CONTRACTION INDEX IN HEART FAILURE
Keywords:
Left ventricular hypertrophy (LVH), left ventricle (LV), heart failure (HF) , myocide, ejection fraction (EF), stroke volume (SV), vascular dysfunction, angiotensin, Ca2 ion.Abstract
Left ventricular hypertrophy (LVH) and concomitant ejection fraction are the most common myocardial structural abnormalities associated with heart failure. LVH is controlled by neurohumoral activation, increased mechanical load, that is, increased pressure on the heart, and arterial hypertension, chronic kidney disease, diabetes, and other cytokines. In this article, we discuss experimental and clinical evidence linking LVH to diastolic dysfunction and establishing it as one diagnostic marker for heart failure.
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