THE IMPORTANCE OF DRUGS ACTING ON ADRENORECEPTORS IN MEDICAL PRACTICE AND THE RELEVANCE OF IMPROVING THEIR USE
Keywords:
Alzheimer's disease, tauopathies, beta amyloid, neurodegeneration, neuroinflammation, adrenergic receptors, adrenergic agonists, adrenergic antagonists.Abstract
Since there are currently no effective disease-modifying medications available, neurodegenerative diseases—of which Alzheimer's disease (AD) is the most common—are among the most debilitating illnesses. The hallmarks of AD, a complex multifactorial neurodegenerative disease, are memory loss and gradual, severe cognitive impairment. It is the most frequent cause of progressive memory loss (dementia) in the elderly, and there is currently no cure or significant slowing of the disease's progression. It is not well known or studied how adrenergic receptors contribute to the pathophysiology of tauopathies, including Alzheimer's disease. Recent research has suggested that medications that target adrenergic receptors may help treat AD and dementias, although overall findings are still unclear because of the variety of pharmacological classes being tried.
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