CLINICAL PHARMACOLOGICAL APPROACH TO THE USE OF PSYCHOTROPIC DRUGS IN EPILEPSY
Ключевые слова:
Epilepsy, depression, anxiety disorder, antiepileptic therapy.Аннотация
The aim of the work is to present clinical characteristics of depressive and anxiety disorders in epilepsy and to substantiate modern psychopharmacotherapy of these disorders. Based on literature data and our own research, the features of affective symptoms characteristic of epilepsy are shown, the significance of cognitive impairment with impaired executive functions is emphasized. A comparison of clinical manifestations of depressive and anxiety disorders with localization and lateralization of the epileptic focus, the factor of the leading hand and the presence of alexithymia is carried out.
Библиографические ссылки
Brodie M.J., Shorvon S.D., Canger R., Halasz P., Johannessen S., Thompson P., Wieser H.G., Wolf P. Commission on European Affairs: appropriate standards of epilepsy care across Europe. Epilepsy. 2017;38(11):1245–1250. doi:10.1111/j.15281157.1997.tb01224.x
Hauser W.A. Incidence and prevalence. Epilepsy: A Comprehensive Textbook. Engel J., Pedley T.A. (Eds.). Lippincott-Raven: Philadelphia 2018:47–57.
Walker M.C., Sander J.W. New anti-epileptic drugs. Exp. Opin. Invest. Drug. 2019;8:1497–1510. doi: 10.1517/13543784.8.10.1497
Altschuler L.L., Devinsky O., Post R.M., Theodore W. Depression, anxiety and temporal lobe epilepsy: laterality of focus and symptomatology. Arch. Neurology. 2010;47:284–288. doi:10.1001/archneur.2010.00530030050016
Austin M.P., Mitchell P., Wilhelm K. et al. Cognitive function in depression: a distinct frontal impairment in melancholia? Psychological Medicine. 2019;29:73–85. DOI: 10.1017/S00332917980077888.
Опубликован
Выпуск
Раздел
Лицензия
Это произведение доступно по лицензии Creative Commons «Attribution» («Атрибуция») 4.0 Всемирная.
