РАННИЕ БИОМАРКЕРЫ ДИАБЕТИЧЕСКОЙ БОЛЕЗНИ ПОЧЕК
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Аннотация:
Диабетическая болезнь почек (ДБП) является широко распространенным заболеванием во всем мире. Она представляет собой одно из наиболее распространенных осложнений сахарного диабета (СД) и является ведущей причиной болезни почек в терминальной стадии болезни почек (ТСБП). В его развитии участвуют три фундаментальных компонента: гемодинамическая, метаболическая и воспалительная. С клинической точки зрения, постоянная альбуминурия в сочетании с прогрессирующим снижением скорости гломерулярной фильтрации (СКФ) определяет это заболевание. Однако, поскольку эти изменения не являются специфичными для ДБП, необходимо обсудить новые биомаркеры, возникающие в процессе патогенеза заболевания, которые могут помочь в диагностике, наблюдении, лечении и прогнозе заболевания.
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