THE SIGNIFICANCE OF IMMUNOCOMPLEX MECHANISMS DURING CHRONIC GLOMERULONEPHRITIS
Abstract
A high level of circulating immune complexes in patients with
glomerulonephritis is observed in connection with the activation of the immune response to
pathogenic antigens, and with a decrease in the mechanism of their elimination. The latter
may also be associated with a weakening of the function of cells of the monocyte-macrophage
system -cells that eliminate immune complexes. The presence of a high CIC index in chronic
GN is an alarming sign indicating an ongoing immuno-inflammatory process in the body
References
A high level of circulating immune complexes in patients with
glomerulonephritis is observed in connection with the activation of the immune response to
pathogenic antigens, and with a decrease in the mechanism of their elimination. The latter
may also be associated with a weakening of the function of cells of the monocyte-macrophage
system -cells that eliminate immune complexes. The presence of a high CIC index in chronic
GN is an alarming sign indicating an ongoing immuno-inflammatory process in the body
