BOLALARDA DISMETABOLIK SINDROMNING IMMUNOLOGIK XUSUSIYATLARI
Abstrak
Dismetabolik sindrom (DS) – bu metabolik buzilishlar majmuasi bo‘lib, u nafaqat endokrin va yurak-qon tomir tizimlariga, balki immun tizimga ham salbiy ta’sir ko‘rsatadi. So‘nggi yillarda bolalarda bu sindrom bilan birga yallig‘lanish markerlarining faolligi ortayotgani kuzatilmoqda. Bu esa immunologik omillarni DS rivojlanishida asosiy patogenetik bo‘g‘inlardan biri sifatida ko‘rib chiqishga asos beradi.
Iqtiboslar
Pierce L. C., Yu Y., Pickering R. T., et al. (2021). Pediatric metabolic syndrome and immune system dysregulation: A review of cytokine involvement. Frontiers in Pediatrics, 9:743628. https://doi.org/10.3389/fped.2021.743628
Fernández-Ruiz K. A., Núñez J. L., Gómez-Álvarez M. (2020). Inflammatory biomarkers in children with metabolic syndrome: A systematic review. Journal of Pediatric Endocrinology and Metabolism, 33(6):783–790. https://doi.org/10.1515/jpem-2019-0481
Alsaedi A., Alabdulkarim Y., Alnasyan S., et al. (2022). Immune response alterations in obese children with metabolic syndrome. Pediatric Research, 92(1):84–91. https://doi.org/10.1038/s41390-021-01768-z
Reinehr T., Roth C. L. (2019). Inflammatory markers in children and adolescents with type 2 diabetes and the metabolic syndrome. Hormone Research in Paediatrics, 91(3):171–178. https://doi.org/10.1159/000499747
