OPTIMIZATION OF THE COMPOSITION AND IMPROVEMENT OF THE MANUFACTURING METHODS OF “GEPAGAL” CAPSULES
Keywords:
Dry plant extract, biologically active supplement, gelatin capsule, technology, composition, excipients, technological properties, quality indicators.Abstract
In recent years, the demand for medicinal plant raw materials in the production of pharmaceuticals, therapeutic cosmetics, and biologically active supplements (BAS) has significantly increased. Compared with synthetic analogues, herbal-based products have notable advantages, including a wide spectrum of therapeutic effects and reduced risk of adverse reactions. In this context, the hepatoprotective dry extract “GEPAGAL” was developed at the Tashkent Pharmaceutical Institute. The aim of this study was to optimize the composition of “GEPAGAL” capsules and improve their manufacturing technology to ensure quality, safety, and therapeutic efficiency.
References
Shodieva N.B., Yunusova H.M. Studies on studying the biopharmaceutical properties and stability of "STIGER-S" tablet// Pharmaceutical Bulletin of Uzbekistan. – 2017. No. 2. B. 10-15.
Maksudova F.X . Biopharmaceutical studies of combined capsules of nonsteroidal antiinflammatory action// Farmasevticheskiy jurnal. - Tashkent. - 2016.-No. 1. -S.88-91
Pinto MV, Oliveira EM, Martins JL, de Paula JR, Costa EA, da Conceição EC, Bara MT. Obtaining a Dry Extract from the Mikania laevigata Leaves with Potential for Antiulcer Activity. Pharmacogn Mag. 2017 Jan-Mar;13(49):76-80. doi: 10.4103/0973-1296.197640. PMID: 28216886; PMCID: PMC5307918.
