MODELLASHTIRILGAN HAYVONLARDA HUJAYRA KELIB CHIQISHINI O‘RGANISH
Keywords:
modellashtirilgan hayvonlar, hujayra kelib chiqishi, differensiatsiya, proliferatsiya, transgen hayvonlar, molekulyar mexanizmlar.Abstract
Mazkur maqolada modellashtirilgan laboratoriya hayvonlarida hujayra differensiatsiyasi va proliferatsiyasi jarayonlarini o‘rganish usullari, mexanizmlari hamda ularning klinik ahamiyati chuqur tahlil qilingan. Tadqiqotlarda ishlatiladigan usullar, molekulyar mexanizmlar, signal uzatish yo‘llari va modellar tavsiflangan.
References
Gilbert, S.F. Developmental Biology, 12th Edition. Sinauer Associates, 2019.
Rossant, J., Tam, P.P. Exploring Early Human Embryo Development. Science, 360(6393), 1075-1078, 2018.
Alberts, B. Molecular Biology of the Cell, 6th Edition. Garland Science, 2014.
Lodish, H. et al. Molecular Cell Biology, 8th Edition. W.H. Freeman, 2016.
Hsu, P.D., Lander, E.S., Zhang, F. Development and Applications of CRISPR-Cas9 for Genome Engineering. Cell, 157(6), 1262-1278, 2014.
