DYNAMICS OF COGNITIVE IMPAIRMENT IN PATIENTS WITH LACUNAR STROKE
Abstrak
Cognitive impairment is one of the most common manifestations of organic brain diseases. The mechanism of formation of cognitive insufficiency is primarily associated with arterial hypertension and atherosclerosis of the extra- and intracranial arteries. Uncontrolled hypertension leads to secondary changes in the vascular wall of lipogialinosis, which develops mainly in the vessels of the microvasculature in the pool of penetrating arteries. Arteriolosclerosis that develops as a result leads to hypoperfusion in the zones of terminal circulation, that is, in deep cerebral structures with the development of focal neurological symptoms, as well as cognitive disorders.
Iqtiboslar
Maksimova M.Yu. Small deep (lacunar) cerebral infarcts in arterial hypertension and atherosclerosis: Autoref. dis.... Dr. honey. sciences. - M., 2002. - 50 s.
Bezerra DC, Sharrett AR, Matsushita K, et al. Risk factors for lacune subtypes in the Atherosclerosis risk in communities (ARIC) study. Neurology 2012;78:102–8.
Caplan LR. Intracranial branch atheromatous disease: a neglected, understudied, and underused concept. Neurology 1989;39:1246–50.
Fisher CM. Lacunes: small, deep cerebral infarcts. Neurology. 1965;15: 774–784.
Inzitari D, Eliasziw M, Sharpe BL, et al. Risk factors and outcome of patients with carotid artery stenosis presenting with lacunar stroke. North American symptomatic carotid endarterectomy trial ground.
