PATHOGENETIC ASPECTS AND ETIOLOGICAL STRUCTURE OF HYPERBILIRUBINEMIA SYNDROME IN THE NEONATAL PERIOD
Ключевые слова:
Neonatal jaundice, hyperbilirubinemia, bilirubin metabolism, UDP-glucuronosyltransferase, hemolysis, liver transport proteins, enterohepatic circulation, genetic polymorphism, bilirubin encephalopathy.Аннотация
Hyperbilirubinemia in newborns is a complex clinical and biochemical syndrome caused by multifactorial disorders of bilirubin metabolism in the early postnatal period. The modern understanding of the pathophysiology of this condition is based on the integration of fundamental knowledge about the molecular and cellular mechanisms of formation, transport, conjugation, and elimination of bilirubin.
Библиографические ссылки
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