OBSTRUCTIVE LARYNGITIS: EFFICACY OF ANTIBACTERIAL DRUGS IN CHILDREN.
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Abstract:
To study the effectiveness of antibiotic therapy in the treatment of obstructive laryngitis (croup) in children. A retrospective analysis of the case histories of 163 children aged 3 months to 5 years who were admitted to the State Clinical Hospital No. 3 in Tashkent for the period from 2019 to 2021 with a diagnosis of obstructive laryngitis was carried out. All children, depending on the severity of croup, were divided into 4 groups and all of them received antibiotic therapy. The comparison group consisted of 22 children with mild to moderate croup who did not receive antibiotic therapy. The effectiveness of antibiotic therapy was assessed by the timing of the disappearance of the clinical symptoms of the disease: the normalization of body temperature, the disappearance of symptoms of intoxication, shortness of breath, cough, restoration of voice, the duration of inpatient treatment.
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Баранов А.А., Таточенко В.К., Бакрадзе М.Д. Лихорадящий ребенок. Протоколы диагностики и лечения. Под общ. ред. А.А. Баранова, В.К. Таточенко, М.Д. Бакрадзе. М.: Педиатр. 2017: 53-61.
Геппе Н. А. и др. Острый обструктивный ларингит (круп) у детей: диагностика и лечение (по материалам клинических рекомендаций) // РМЖ. Мать и дитя, 2014. №14.
Минин Ю.В., Кучеренко Т.И. К вопросу о тактике лечения комбинированного стеноза гортани. // Журнал ушных, носовых и горловых болезней. 2008. - №5. – С. 63-67.
Полякова А.С., Бакрадзе М.Д., Таточенко В.К. Синдром крупа у детей: предрассудки и доказательная медицина. Фарматека. 2018;1(354):15-22.
Савенкова М. С. Современные аспекты этиопатогенеза и тактики ведения детей с острым стенозирующим ларингитом. // Педиатрия. – М., 2008. - №1. – С. 133-138
Kong K-F., Schneper L., Mathee K. Beta-lactam Antibiotics: From Antibiosis to Resistance and Bacteriology // APMIS: actapathologica, microbiologica, etimmunologica Scandinavica. 2010. 118 V 1. P. 1-36. DOI: 10.1111/j.1600-0463.2009.02563.x.
King D.T., Sobhanifar S., Strynadka N.C.J. One ring to rule them all: Current trends in combating bacterial resistance to the beta-lactams // Protein Science. 2016. V. 25, № 4. P. 787-803. DOI: 10.1002/pro.2889.
Roca I., Akova M., Baquero F., et al. The global threat of antimicrobial resistance: science for intervention // New Microbes and New Infections. 2015. №. 6. P. 22-29. DOI: 10.1016/j.nmni. 2015.02.007.
Nikaido H. Multidrug Resistance in Bacteria // Annual review ofbiochemistry. 2009. № 78. P. 119-146.

