EVALUATION OF THE EFFECTIVENESS OF H2 HISTAMINE RECEPTOR BLOCKERS IN THE RATIONAL PHARMACOTHERAPY OF GASTROINTESTINAL TRACT DISEASES
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Abstract:
Gastrointestinal tract diseases (gastritis, gastric, and duodenal ulcers) are widespread worldwide and have serious socio-economic consequences. This study evaluated the effectiveness of H2 histamine receptor blockers in pharmacotherapy. The clinical status, complaints, laboratory tests, and endoscopic findings of patients were analyzed to assess treatment outcomes. The results demonstrated that H2 blockers effectively reduce gastric acid secretion, accelerate the healing process of ulcers, and alleviate clinical symptoms. The findings confirm the effectiveness of H2 blockers in the treatment of gastrointestinal tract diseases and support their use in rational pharmacotherapy.
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References:
Malfertheiner P., Chan F.K., McColl K.E.L. Peptic ulcer disease. Lancet. 2009;374:1449–1461.
Numonova G.D. Etiopathogenesis of gastrointestinal diseases. Multidisciplinary Journal of Science and Technology. 2025; Uzbekistan, ASMI.
Sobirjonov I.T. Specificity of treatment of peptic ulcer disease with H2 histamine blocker drugs. Multidisciplinary Journal of Science and Technology. 2025; Uzbekistan, ASMI.
Sachs G., Shin J.M. The pharmacology of H2-receptor antagonists. Aliment Pharmacol Ther. 2008;27:3–8.
Vakil N., et al. Gastroesophageal reflux disease: epidemiology and clinical features. Am J Gastroenterol. 2006;101:60–74.
Lanza F.L., et al. Guidelines for prevention of NSAID-induced ulcers. Am J Gastroenterol. 2009;104:728–738.
Baron T.H., et al. Peptic ulcer disease and H. pylori. N Engl J Med. 2010;362:1597–1608.

