Евразийский журнал медицинских и естественных наук

This comprehensive article explores the multifaceted aspects of Cleft Lip and Palate, congenital conditions affecting facial and oral structures during fetal development. Delving into causes, symptoms, and diagnostic methods, it illuminates the challenges faced by individuals with these conditions. Surgical interventions, orthodontic solutions, and supportive therapies are presented as effective avenues for treatment. The article also probes into the emotional and social impact of cleft lip and palate, emphasizing the importance of support networks for affected individuals and their families. In essence, it serves as a valuable resource for understanding, addressing, and navigating the complexities associated with cleft lip and palate, contributing to a holistic approach to care and support.

Печень является ключевым органом, обеспечивающим все энергетические и пластические потребности, осуществляет детоксикацию эндогенных и экзогенных веществ путем их трансформации в конечные продукты обмена. Последнее время в общей структуре заболеваний большую долю занимает патология гепатобилиарной системы.

Хронический пиелонефрит — это длительное воспаление почек, особенно почечных канальцев и окружающих структур. Обычно это вызвано рецидивирующими инфекциями мочевыводящих путей, которые распространяются на почки. У детей это может чаще встречаться у лиц с врожденными аномалиями мочевыводящих путей или состояниями, нарушающими отток мочи.

При исследовании  особенностей  клинической картины ишемического инсульта в зависимости от наличия сердечной патологии у 182 пациента (95 женщин и 87 мужчин) в возрасте от 41 до 79 лет в острейшем и остром периодах ишемического инсульта (ИИ) в бассейне средней мозговой артерии (СМА), было выявлено, что общемозговая и очаговая симптоматика инсульта была более выраженной, а общее состояние чаще было тяжелым у пациентов с ИБС, особенно у лиц женского пола.

Провести анализ лабораторных нарушений у больных с аутоиммунной гемолитической анемией, в зависимости от степени тяжести.

62 donors aged from 20 to 55 years (33 men and 29 women) were examined. Among them, 29 people (17 men and 12 women) donated for the first time in their lives - they made up the first (I) observation group, and 33 donors (17 men and 16 women) were regular donors with a donation experience of more than two years and did not less than two donations annually—they formed the second (II) observation group. The article presents the results of a study of the morphological characteristics of erythrocytes in active blood donors and some parameters that characterize the physical properties of erythrocytes. It was concluded that active donation may be accompanied by changes in a number of morphological and physical characteristics of red blood cells.

This article provides a comprehensive exploration of diabetes mellitus in newborns, delving into its causes, diagnostic methods, and treatment options. By highlighting the genetic and autoimmune factors contributing to neonatal diabetes, it offers valuable insights for medical professionals. The discussion on clinical symptoms and genetic testing aims to enhance early detection, enabling prompt intervention. Emphasizing the significance of insulin therapy and long-term management, the article addresses the complex nature of diabetes in newborns. Additionally, it underscores the potential impact on developmental aspects, advocating for proactive measures and holistic care. Overall, the article serves as an informative guide for healthcare professionals and families navigating the intricacies of diabetes mellitus in the neonatal context.

Кариес зубов – одно из распространенных заболеваний твердых тканей зубов, особенно в детском возрасте. Несмотря на то что, вопросам развития и совершенствования методов профилактики кариеса уделяется большое внимание, его распространённость и интенсивность остается достаточно высокой. Психоэмоциональные, физические и интеллектуальные нагрузки, которые испытывают старшеклассники способствуют началу развития заболеваний или обострению хронической патологии. Наряду с психоэмоциональным напряжением страдает стоматологическое здоровье школьников. Анализ показателей, оценивающих состояние твердых тканей зубов, выявлена прямая корреляционная связь между распространенностью и интенсивностью кариеса зубов и наличием психоэмоционального напряжения.

XX-XXI asrning oxirida dunyo hamjamiyati nafaqat tibbiy, balki katta ijtimoiy-iqtisodiy ahamiyatga ega bo'lgan global muammoga - surunkali kasalliklar pandemiyasiga duch keldi. Qandli diabet, yurak, o'pka, buyrakning surunkali kasalliklari, shuningdek ularning turli kombinatsiyalari sayyoramizning har bir bosqinchisida qayd etilgan. Yuqori texnologiyali intensiv va o'rinbosar terapiya usullari hayotni saqlab qolishi mumkin, lekin har doim ham - uning sifatini, mehnat qobiliyatini va ijtimoiy faolligini saqlab qolish uchun. Shu bilan birga, oddiy va arzon profilaktika usullari juda samarasiz qo'llaniladi, kasallik kech aniqlanadi va davolash afsuski, bemorlar uchun motivatsiya va sog'lom turmush tarziga sodiqlik yo'q. Buyrak shikastlanishining erta klinik va laboratoriya belgilari ko'pincha xiralashgan ko'rinishga ega va shifokorning hushyorligini, ayniqsa, keksa bemorlarda bo'lsa, ogohlantirmaydi. Buyrak kasalligining dastlabki belgilari "yosh normasi" deb hisoblanadi.

Hozirgi kunda jigar alkogolsiz yog‘ kasalligi sog'liqni saqlash tizimining dolzarb muammolaridan biri hisoblanadi. So'nggi yillarda tibbiyotda qo'llaniladigan yangi diagnostika usullari va dori vositalari kashf etilganiga qaramay, JAYKning etiopatogenezi, diagnostikasi, davolash va oldini olish bo'yicha hal qilinmagan ko'plab masalalar mavjud. Jigar alkogolsiz yog‘ kasalligini davolashning asosiy maqsadi kasallikning keyingi bosqichlariga rivojlanishining oldini olish bo'lishi kerak. Klinika amaliyotida ishlatiladigan asosiy jigar testlari kasallik uchun spetsifik emas  va har doim ham gistologik o'zgarishlar (jarohatlanish, yallig'lanish, fibroz) haqida aniq ma’lumot bera olmaydi, biopsiya esa jigar kasalliklari  diagnostikasida "oltin standart" hisoblanib, JAYK ida kasallikning rivojlanish bosqichlarini, terapevtik ta'sirning samaradorligini belgilaydi. Ushbu maqolada biz klinik amaliyotda JAYK va jigar fibrozi diagnostikasi uchun ishlatiladigan invaziv bo'lmagan biomarkerlar haqida to'xtalib o'tamiz. MikroRNK ning jigar alkogolsiz yog‘ kasalligining rivojlanishidagi potentsial roli muhokama qilinadi.

Pnevmokoniozning bir turi hisoblangan silikozning etiologik omili kremniy dioksididir. Oʻpka silikozining rivojlanishi oʻziga xos jarayon boʻlib, unda alveolyar makrofaglar tomonidan kremniy dioksidi zarralarini yutish va ularning chiqarilishi yalligʻlanishni, tugunli shikastlanishlar va qaytarilmas fibrozni keltirib chiqaradi. Silikozning patofiziologiyasi murakkab boʻlib, patogen mexanizmlar oʻrtasidagi oʻzaro ta’sir toʻliq oʻrganilmagan.  Ushbu maqola silikozning patofiziologiyasi boʻyicha yangi ma’lumotlarni koʻrib chiqadi.

В статье представлена информация о течении синдрома раздраженного кишечника у подростков, его причинах, диагностике и лечении.

Papaveraseae oilasi mansub Papaver angrenicum (angren ko‘knorisi) o‘simligi tarkibidagi alkaloidlar saqlash dinamikasi o‘simlikni o’sish davriga qarab aniqlandi. Alkaloidlar yigindisida birinchi marotaba yangi alkaloid ajratib olindi va uni pangrenin deb nomlandi. Pangrenin tuzilishi IQ, Mass, YaMR va roentgen strukturaviy analiz yordamida isbotlandi.

Неонатальный сепсис — серьезное заболевание, при котором возбудители проникают в кровоток, размножаются и производят токсины, оказывая вредное воздействие на здоровье новорожденных. В зависимости от времени возникновения его делят на два типа. Сепсис с ранним началом возникает в течение 72 часов после рождения, а сепсис с поздним началом начинается через 72 часа после родов.

Bolalarda Cl miqdorining ko'payishi va jarayonning og’irligi bolaning reaktivligiga bog’liqligi va gomeostazni himoya qilish tizimlarining o’ziga xos va o’ziga xos bo’lmagan reaktivligining o’zgarishi yuqumli jarayonning rivojlanishining birinchi va asosiy sharti ekanligi to’g’risida ishonchli ma’lumotlar tobora ko’payib bormoqda. Shu munosabat bilan bizning keyingi vazifamiz Cl bilan zararlangan yosh bolalarning immunologik reaktivligiga endogen intoksikatsiyaning ta’sirini o’rganish edi.

This essay explores the dynamic changes in vision across different stages of life, highlighting age-related transformations in the human visual system. From the sharp visual acuity of childhood and peak performance in young adulthood to the onset of presbyopia, cataracts, and condit ions like age-related macular degeneration (AMD) and glaucoma in later years, the essay delves into the intricacies of how eyesight evolves over time. It addresses common age-related visual changes such as presbyopia, cataracts, AMD, glaucoma, dry eye syndrome, and retinal detachment, emphasizing the importance of awareness, regular eye examinations, and proactive care in preserving and optimizing vision throughout the aging process.

This comprehensive essay delves into the intricate landscape of Coronary Heart Disease (CHD), a global health challenge impacting millions worldwide. It explores CHD's definition, risk factors, symptoms, diagnostic approaches, treatment strategies, preventative measures, global impact, and public health initiatives. The essay emphasizes the interplay of modifiable and non-modifiable risk factors, the diverse clinical manifestations of CHD, and the importance of early detection and intervention. Additionally, it underscores the collective imperative of global efforts, including public health initiatives, to address the burden of CHD on a larger scale.

This article delves into the nuanced transformations in bone composition between children and adolescents, examining the dynamic processes that underlie skeletal development. It explores the pivotal role of the growth plate in childhood bone formation, the mineralization dynamics involving calcium and phosphorus, and the shift towards bone remodeling during adolescence. Hormonal influences, particularly during puberty, and the attainment of peak bone mass are discussed, shedding light on the critical milestones in bone development. Lifestyle factors, including nutrition and physical activity, are highlighted, and the clinical implications of understanding these differences are addressed, emphasizing the importance of monitoring and optimizing bone health during these formative stages.

This in-depth article provides a comprehensive exploration of duodenitis, an inflammatory condition affecting the duodenum—the initial portion of the small intestine. Covering diverse aspects such as definition, causes, symptoms, diagnosis, treatment strategies, potential complications, and preventative measures, it aims to offer a nuanced understanding of this gastrointestinal ailment. The article emphasizes the multifactorial nature of duodenitis, spanning infections, irritants, and autoimmune responses, and outlines a range of symptoms that characterize its presence. Diagnostic methods, including endoscopy and biopsy, are discussed, along with tailored treatment approaches such as antibiotics and lifestyle adjustments. The narrative also delves into complications, long-term management, and strategies for preventing duodenitis, underscoring the importance of seeking professional guidance for accurate diagnosis and treatment..

This expansive essay provides an in-depth exploration of skin-related problems, ranging from common irritations to chronic conditions. It comprehensively covers the multifaceted nature of the skin, delving into its structure and functions. The essay addresses prevalent skin issues, such as acne, eczema, psoriasis, dermatitis, and rosacea, unraveling their etiology, triggers, and symptomatic manifestations. Diagnostic approaches, including visual examination, skin biopsy, and patch testing, are discussed, alongside diverse treatment modalities, such as topical and oral medications, phototherapy, and lifestyle adjustments. Chronic skin conditions and their long-term management are highlighted, emphasizing the importance of regular follow-ups and emotional support. Prevention strategies and holistic skincare practices are detailed, promoting sun protection, hydration, and gentle cleansing. The essay concludes by advocating for seeking professional guidance and empowering individuals to embrace optimal skin health and resilience.

This academic article offers a thorough exploration of wisdom teeth in humans, addressing their evolutionary significance, anatomical variations, and clinical implications. The interdisciplinary approach encompasses evolutionary biology, dental anatomy, and clinical dentistry. The article examines the evolutionary roots of wisdom teeth, their diverse anatomical characteristics, and the clinical challenges associated with their development, eruption, and potential complications. By providing insights into the historical context, anatomical intricacies, and contemporary clinical considerations, this article serves as a comprehensive resource for researchers, clinicians, and scholars interested in understanding the enigma of wisdom teeth.

This informative article delves into the multifaceted functions of sphincters in the human body. Acting as dynamic gatekeepers, sphincters are circular muscles strategically placed in various organs and systems to regulate the controlled flow of substances. The article explores the anatomy and different types of sphincters, ranging from muscular and smooth muscle sphincters to striated muscle sphincters, each serving unique roles. It delves into specific sphincters within the gastrointestinal, urinary, reproductive, cardiovascular, and respiratory systems, elucidating their roles in maintaining homeostasis. The article also addresses the crucial role of sphincters in preventing disorders and dysfunctions, emphasizing their significance in clinical interventions. By providing a comprehensive overview, this article serves as a valuable resource for understanding the intricate functions of sphincters in the human body.

This comprehensive essay explores the intricate world of dysbacteriosis, a condition characterized by an imbalance in the gut microbiota. It delves into the fundamental role of bacteria in the gut and how dysbacteriosis disrupts this delicate balance. The essay covers the causes and contributing factors, consequences on digestive and overall health, diagnostic approaches, and potential interventions. By examining the complex interplay between the gut and various influencing factors, this essay provides valuable insights into the implications of dysbacteriosis and strategies for maintaining gut health.

This article delves into the captivating realm of brain development in newborns, exploring the intricacies of the early stages of cognitive, emotional, and motor growth. It covers the structural components of the neonatal brain, the dynamic processes of synaptic growth and pruning, and the influence of sensory stimulation on neural connections. The article also addresses motor milestones, critical periods, the social and emotional foundations fostered through bonding, and the resilience of the developing brain in the face of challenges. Furthermore, it touches upon the role of genetics and epigenetics in shaping the newborn brain. The aim is to provide a comprehensive understanding of the foundational processes that contribute to the formation of the human mind in its earliest stages..

This comprehensive essay provides an in-depth exploration of Acquired Immunodeficiency Syndrome (AIDS), tracing its historical roots, examining the virology of Human Immunodeficiency Virus (HIV), and analyzing the global epidemiology of the pandemic. The essay delves into the societal impact of AIDS, discussing the enduring challenges of stigma and discrimination. It highlights the transformative impact of medical advancements, such as antiretroviral therapy (ART), and addresses ongoing challenges in the fight against AIDS. The essay concludes with a forward-looking perspective, considering future prospects, global initiatives, and the continued journey towards eradicating AIDS.

This comprehensive article delves into the multifaceted world of the central nervous system (CNS), encompassing the brain and spinal cord. It explores the intricate anatomy and functions of the CNS, shedding light on sensory processing, motor control, cognitive functions, and autonomic processes. The article also delves into neural communication, the protective mechanisms safeguarding the CNS, and the dynamic nature of neuroplasticity. Disorders affecting the CNS, diagnostic techniques, therapeutic interventions, and the future of CNS research are thoroughly examined. By providing a holistic overview, this article serves as an insightful resource for understanding the pivotal role of the CNS in orchestrating the complexities of the mind and body.

Oziqlanish saraton rivojlanishiga ta’sir qilgani kabi, saraton ham insonning ovqatlanish holati, oziq-ovqat iste’moli va ishtahasiga ta’sir qiladi. Saratonni davolashda qo‘llaniladigan radioterapiya va kimyoterapiya kabi usullar ozuqa moddalari va energiyaga bo‘lgan ehtiyojni oshiradi. Ushbu ortib borayotgan ehtiyojlarga muvofiq, yetarli va muvozanatli ovqatlanish davolanishga chidamlilikni oshiradi, nojo‘ya ta’sirlarni yengishni osonlashtiradi, tanamizning immunitet tizimini mustahkamlaydi, sog‘lom hujayralarni himoya qilishga yordam beradi va vazn yo‘qotishning oldini oladi. Shu sababli ham saraton kasalligining oldini olishda ham, davolash jarayonida ham to‘yimli va ratsional ovqatlanish katta ahamiyatga ega.

В настоящее время сапонины корней колючелистника качимовидного могут быть использованы в пищевой промышленности в качестве природных эмульгаторов при производстве различных типов майонезной продукции, а также активных пенообразователей при производстве халвы и щипучих напитков, кондитерских кремов, муссов и мороженного. В то же время, создание культивируемой сырьевой базы колючелистника качимовидного сопряжено с немалыми трудностями, невозобновляемость подземных органов и их малодоступность для обширных исследований наладывают определенные ограничения и обуславливают необходимость проведения работ по поиску альтернативных источников.

Ushbu maqolada Respublikamiz paxtachiligida zamonaviy texnologiya asosida kislota bilan tuksizlantirilib tayyorlangan urug’lik chigitlarni ekishning dala unuvchanligiga, go’za nihollarining gommoz, ildiz chirish kasalliklari va hosidorlikka samarali ta’siri haqidagi ma’lunotlar keltirilgan. O’tkazilgan tajribada boshqa variantlarga qaraganda ijobiy natijalar asosan kislota yordamida tuksizlantirilgan “Vitavaks – 200 FF” urug’ dorisi bilan 5 l/t dorilanib ekilgan variantda kuzatildi. Bu variantda dala unuvchanligi 6 % ga oshganligi, gommoz kasalligi sezilarli bartaraf etilganligi, ildiz chirish 3,5 baravarga kamayganligi, hosildorlik esa ҳар гектардан 2,8 sentnerga ko’payganligi aniqlandi.

Данное научное исследование посвящено обзору сигнальных путей RAS, фундаментальных молекулярных механизмов, играющих ключевую роль в регуляции клеточных процессов. Анализировались структура и функции генов RAS, взаимодействие белков, активация сигнальных каскадов, а также их роль в различных патологических состояниях, включая рак. Рассматривается сложность и разнообразие сигнальных путей RAS в контексте различных клеточных типов, а также обсуждаются перспективы терапии и возможности воздействия на эти молекулярные механизмы в целях лечения заболеваний.

This comprehensive article explores the multifaceted functions of the body's joints, ranging from facilitating movement and providing stability to supporting daily activities and contributing to overall musculoskeletal health. It delves into the diverse types of joints, including synovial, cartilaginous, and fibrous, elucidating their structures and roles. The article emphasizes the importance of joint health, considering aspects such as shock absorption, load-bearing, and the impact of aging on joint function. Additionally, it discusses common joint disorders, rehabilitation strategies, and the vital role of physical therapy in restoring joint function. This article serves as a valuable resource for understanding the integral role joints play in the harmonious symphony of human movement.

Данная статья исследует важности роли микрофлоры кишечного тракта в формирование и развитие иммунной системы человеческого организма. В последнее время усердно изучается влияние бактерий кишечного тракта на иммунную защиту организма. В пищеварительном отделе человеческого организма и прочих млекопитающих находятся множество групп бактерий, большинство из них которые являются бактериями-симбионтами.

This comprehensive article provides an in-depth exploration of skull anatomy, covering various aspects, including the structure and functions of cranial and facial bones, sutures, foramina, and internal structures. It delves into developmental anatomy, clinical significance, and common pathologies related to the skull. The article aims to offer a holistic understanding of the human skull, from its intricate components to its functional significance.

This work is devoted to the use of pomegranates in folk medicine, as well as the chemical composition and applications.

This comprehensive essay delves into the multifaceted landscape of bowel disorders and conditions, offering a thorough exploration of prevalent issues affecting digestive health. From the common disruptions of irritable bowel syndrome (IBS) to the complexities of inflammatory bowel disease (IBD) and the significance of gastrointestinal cancers, the essay navigates through etiology, symptoms, and management strategies. The inclusion of constipation and diarrhea, two prevalent gastrointestinal concerns, adds a holistic perspective to bowel health. The essay emphasizes the importance of understanding these conditions for early detection, effective management, and enhanced quality of life.

Ushbu maqola bo’g’im kasalliklarini davolashda asalari zaxarining (apitoksin) shifo samarasi uni bo’g’imlarga va organizmga ta’sir samarasi yoritiladi. Asalari chaqtirib davolash boshqz tur davolash usullaridan afzalliklari ko’rsatiladi.