Eurasian Journal of Medical and Natural Sciences

At present, the prevalence of type 2 diabetes mellitus (DM-2) is steadily increasing. Surgical methods of treatment (restriction and shunting operations) occupy a leading position in the treatment and correction of this pathology due to the highest metabolic efficiency. Each of the existing shunting operations (gastric gastrointestinal, biliopanсreatic bypass (PBS)), in turn, is used in various modifications. Among the operations of BPS are known modifications of Scopinaro, modification of Hess-Marceau and SADI appeared in recent years (duode-iliac bypass with gastric resection and one anastomosis).

In the article, the content analysis of antihistamine drugs is carried out in several directions, the current state of their use in our Republic and their prospects are presented. The significance of the analysis of antiallergic drugs in the modern pharmacotherapy of allergic diseases, their classification by chemical structure and genera, and the nomenclature of antihistamines were studied by country.

Patients with nonspecific interstitial pneumonia (NSIP) are typically obese or overweight due to impairment in daily living activities and the side effects of prednisone. This study aimed to elucidate the effect of weight loss on pulmonary function test (PFT) in obese NSIP patients.

Gingivitis in pregnant women is a gum disease characterized by swelling and bleeding. Approximately 60% of pregnant women develop this disease [1]. A special feature of gingivitis in pregnant women is its cause, which is associated with hormonal changes that occur in the body during pregnancy. Hormonal fluctuations characteristic of this period can provoke the development of slight inflammation of the oral mucosa, making it especially sensitive. When brushing your teeth, the gum tissue becomes more vulnerable and susceptible to damage, which leads to bleeding [2]. Despite ongoing research, the features of the development of inflammatory periodontal diseases in pregnant women still remain insufficiently studied. In this regard, prevention, diagnosis and treatment of gingivitis in pregnant women remain insufficiently effective [3]. Moreover, during pregnancy, many therapeutic methods and medications cannot be used or can only be used if the risk to the health of the mother or fetus is comparable to the risk of developing gingivitis.

Bugungi ilm-fan shiddat bilan taraqqiy etib borayotgan zamonda barcha sohalar qatori farmasevtika sohasi ham rivojlanib bormoqda. Ayni vaqtda kasalliklar orasida turli xil asab tizimi bilan bog‘liq muammolar salmoqli o‘rin egallaydi. Mazkur patologik holatlarni yengillashtirish maqsadida bir qancha dori preparatlari yaratilgan Mazkur maqolada ayni preparatlardan biri pregobalin dori vositasining toksikologik ahamiyati mavjud manbalar asosida atroflicha yoritib berilgan.

The paper presents an analysis of data on restoring natural fertility in women with infertility due to endometriosis to increase the effectiveness of infertility treatment. The purpose of the study was to improve the effectiveness of infertility treatment by methods of restoring natural fertility in patients with external genital endometriosis. According to the results of the survey, rational treatment of infertility in patients with stage I-II endometriosis of the external genitalia allows natural restoration of fertility in 40.2% of cases.

Mummy was analyzed by atomic absorption spectrophotometry and chromatography-mass spectrometry (GC-MS). The presence of a number of active metals, biologically and chemically active substances was checked, and it was found that their use in medicine in various diseases justified itself.

High numbers, wide distribution, high species diversity, low mobility and insignificant ability to overcome geographical barriers, ease of collecting material and sensitive response to changes in the external environment make the group of terrestrial mollusks a convenient object of biogeographical and ecological research.

Objective: to study the mid-term and long-term results of using the new generation of BVS-scaffold Magmaris in patients with acute coronary artery disease.

This article will discuss the prevention of vitamin D deficiency in children. Vitamin D is part of the group of fat-soluble vitamins and is involved in the absorption of calcium and phosphorus, which are necessary for the strength of bones and teeth in children and adolescents. Vitamin D also supports the immune system, helping the body fight infections and inflammation. Prevention of vitamin D deficiency is becoming relevant today.

Protein-energy malnutrition (PEM) is a pathological condition that is characterized by a deficiency of nutrients and energy and negatively affects the functioning of all body systems. The main signs of the pathology are loss of more than 10% of the initial weight in a short period of time, asthenovegetative syndrome, dryness and pallor of the skin. Diagnostics includes performing a physical examination and laboratory tests to assess the patient’s condition, instrumental methods to determine the root cause of nutritional deficiency.

The study was devoted to studying modern views on the problem of sensitivity to latex among medical workers. Sensitization to latex can occur by aerogenic, contact, parenteral, alimentary routes; the risk group includes healthcare workers, food industry workers, catering establishments, utility workers, people with a history of atopy, those who have undergone numerous surgical operations, defects of the nervous system, patients with diseases of the gastrointestinal tract, genitourinary system. It is recommended to improve the working conditions of health workers at risk by reducing all methods of contact with latex.

Hepatitis is a global health concern that affects millions of people worldwide. It is a viral infection that causes inflammation of the liver and can lead to serious health complications if left untreated. In this article, we will explore the different types of hepatitis, their causes, treatment options, and prevention strategies to help raise awareness about this important issue.

The main principle of the diet for food allergies to gluten is the elimination of allergens and allergen components that are characteristic of the region and individually for each patient. The correct tactics for carrying out elimination diets, taking into account the sensitizing properties of foods that contain gluten, is the main method of treatment for food allergies and gluten intolerance.

Acute kidney injury (AKI) is a common occurrence in the neonatal intensive care unit (NICU). In recent years, our knowledge of the incidence and impact of neonatal AKI on outcomes has expanded exponentially. However, treating AKI in newborns is often challenging due to the functional immaturity of the neonatal kidney.

We studied 35 obese children aged 7 to 18 years, as well as 20 children with normal body weight.  A relationship was obtained between the severity of carbohydrate metabolism disorders, dyslipidemia in children and the level of microalbuminuria, which was expressed by an increase in the level of cholesterol, triglycerides, LDL and a decrease in HDL, an increase in immunoreactive insulin and the IR HOMA R index in children with high microalbuminuria.  It was revealed that in children with obesity and microalbuminuria, renal hemodynamic disturbances are determined at the level of the interlobar and arch renal arteries.  A statistically significant decrease in Vmin at the level of large renal vessels allows us to consider these changes as a marker of early disorders of renal hemodynamics.

Pregnancy involves many changes in a woman's body, and changes in the urinary system are no exception. The vast majority of authors directly or indirectly link the development of urinary disorders with pregnancy and childbirth. The study aimed to examine the incidence and nature of urinary incontinence during pregnancy. Pregnant women who applied to the multidisciplinary clinic of SamSMU in 2023 were examined. The study showed that the leading risk factors for all types of urinary disorders during pregnancy are: their presence before the present pregnancy, the age of patients over 35 years, a history of pregnancy, and BMI values > 25 kg/m2.

In this article, the use of garden rows, tillage, watering and fertilizing and mulching of fruit trees, in short, it is necessary to correctly perform agrotechnical activities in gardens. thoughts and comments are made about it. Currently, the main purpose of working the soil is the urgency of regularly increasing its productivity and the need to use it for the cultivation of food products, fodder and technical crops, as well as for the cultivation of as many high-quality products (fruits and vegetables) as possible, and to meet this demand. information on the practical work to be carried out is given.

OBJECTIVES: We adopted perimembranous (PM) ventricular septal defect (VSD) closure by using only femoral arterial access and choosing device size based on transthoracic echocardiography (TTE) without injection of contrast. Here, we have evaluated mid term results.

Дефицит макро- и микроэлементов во время беременности связан с развитием недостаточности питания, прямо и косвенно влияют на развитие плода, а также повышает риск возникновения врожденных аномалий, особенно аномалий нервной трубки. В статье представлена информация о влиянии фолиевой кислоты на развитие плода у беременных, уточнены профилактические дозы и их случаи передозировки.

В стационаре обследованы 120 больных хронической обструктивной болезнью легких в возрасте от 24 до 72 лет (средний возраст – 48,6 лет). Стаж болезни по хронической обструктивной болезнью легких составлял, в среднем, 15,6 лет. Анализ клинического течения ХОБЛ показал, что с утяжелением степени заболевания отмечается не только нарастание интенсивности клинических проявлений заболевания, но и усугублением степени кардио-респираторных нарушений, что характеризуется высокой частотой развития синдрома утомления респираторных мыщц, резкой степени выраженности (96,3%),  нарушениями ритма сердце (76,6%) и гипертрофий правого отдела (36,2%) и наличием P-pulmonale (55,3%), различной степени гипоксемии (75,0%).

Non-alcoholic fatty liver disease (NAFLD) has become a significant public health problem worldwide, representing a spectrum of liver diseases from simple steatosis to non-alcoholic steatohepatitis (NASH), fibrosis, cirrhosis and hepatocellular carcinoma (HC). The global prevalence of NAFLD has reached epidemic proportions, closely paralleling the rising prevalence of obesity, insulin resistance, type 2 diabetes mellitus and metabolic syndrome.

Currently, 80-85% of raw cotton grown in our republic is high-grade cotton. This, in turn, is one of the urgent issues of keeping high-grade cotton with natural quality indicators, drying and cleaning using special modern low-energy techniques. This article talks about the effect of temperature changes on the quality of raw cotton during storage.

to evaluate the relationship between body mass index and compliance in patients with coronary artery disease comorbid with diabetes mellitus.

Urolithiasis occupies one of the leading places in the structure of urological diseases in terms of prevalence, hospitalized morbidity and place among the most common surgical diseases in patients seeking emergency care and emergency admission to the hospital.

The article presents the rich chemical composition of garlic and onions, as well as vitamins, garlic flavonoids allicin garlic contains information that biologically active components of onions, such as quercetin, enhance their healing properties, as well as the prevention and treatment of various diseases of the body with folk remedies.

An experimental study of bioequivalence in terms of acute toxicity and specific activity of the drug "Fordexa" – solution for injection, manufactured by LLC "PHARM PRODUCT" Uzbekistan in comparison with the drug analog "Keiver" - for injection of 50 mg / 2 ml (c 140522, p.1•. 05/2025. No. and date register: DV/X 01551/04/16 01/0416), manufactured by PAT Farmak, Ukraine, showed that the drugs were biologically equivalent and have an equivalent reliable analgesic and anti-inflammatory effect.

This scientific work evaluates the clinical and instrumental features of the course of myocardial infarction during paroxysmal AF, thanks to the combined use of methods for assessing troponin I, ECG, coronary angiography (CAG), and transthoracic echocardiography. The study included 128 patients hospitalized in emergency care departments No. 1 and 2, and cardiac intensive care unit of the Samarkand branch of the Republican Scientific Center for Emergency Medical Care. Paroxysmal AF may develop against the background of a more serious pathology, such as atherosclerotic lesions of the coronary arteries or lead to secondary myocardial damage. Studying troponin levels in this group of patients seems justified.

Аномальные маточные кровотечения распространённая проблема современной гинекологии так как встречается до 30% репродуктивного возраста и 42% в пременопаузе. Данная статья посвящена изучению основных моментов данной патологии и современным достижениям на основе данных мировой и отечественной литературы за последние 5 лет.

Ushbu maqolada sachratqi (Cichorium intybus) o’simligi, uning morfologik tuzilishi, geografik tarqalishi, kimyoviy tarkibi, farmatsevtik xususiyatlari, xalq tabobati va tibbiyotda qo‘llanilishi tahlil qilingan. Hozirgi kunda ko’plab mamlakatlarda sachratqi o’simligining guli, bargi, yosh novdasi, ildizidan turli maqsadlarda foydalanib kelinmoqda.

Безопасный медикаментозный аборт является одним из способов прервать нежелательную беременность с помощью планирования семьи. Снижение ранних и поздних осложнений после аборта и сохранение репродуктивной функции является одной из важных задач в акушерстве и гинекологии. Медикаментозный аборт в области акушерства и гинекологии позволил снизить количество послеродового эндометрита, септических заболеваний, вторичного бесплодия, а также гнойно-септических заболеваний после аборта и материнской смертности. Но профилактика осложнений медикаментозного аборта до сих пор недостаточно изучена. В статье анализируется проблема.

В нашей работе отражены гиперплазии эндометрия в аспекте морфологии на основании литературного обзора.

Ишемическая болезнь сердца и хроническая почечная недостаточность чаще всего встречаются совместно, осложняя друг друга. В корне этого явления лежит такой общий этиологический фактор, как дисфункция эндотелия кровеносных сосудов. Примером может служить атеросклероз кровеносных сосудов, продолжительная артериальная гипертензия и другие патофизиологические механизмы. Атеросклерозу подвергаются сначала периферические кровеносные сосуды, которые изначально могут протекать бессимптомно. Если не начать купировать содержание холестерина в крови, то атеросклероз может распространяться до коронарных и почечных артерий, что даёт характерную симптоматику для этих заболеваний. Ввиду всего вышеперечисленного, совместное изучение ИБС и ХПН является актуальным на сегодняшний день.

Qadimdan dorivor o‘simliklardan insonlar salomatligini   saqlashda foydalanib kelishgan. Shifobaxsh o‘simliklar kasalliklarning oldini olishda muhim rol o‘ynaydi va ularni targ‘ib qilish va foydalanish barcha mavjud profilaktika strategiyalariga mos keladi. Kasalliklarni davolashda o‘simlik dori vositalarini tadqiq qilish va ulardan foydalanish kundan-kunga ortib bormoqda. Dorivor o‘simliklar tabiiy birikmalar mavjudligi sababli dorivor xususiyatlarga ega molekulalarning asosiy manbai hisoblanadi. Dorivor o‘simliklar inson kasalliklarini davolash uchun foydalidir va fitokimyoviy tarkibiy qismlar mavjudligi sababli davolanishda muhim rol o‘ynaydi. Ushbu tadqiqot o‘simliklarning dorivor maqsadlarida foydalanish bo‘yicha bilimlarga va ularning shifobaxsh xususiyatlarini, shuningdek, dorivor o‘simliklarning aholi salomatligi uchun muhim bo‘lgan kasalliklarga qarshi kurashdagi roli, hissasi va foydaliligini tasdiqlash uchun ilmiy tadqiqotlarga qaratilgan.

Гипокалиемия является одним из  наиболее распространенным нарушением электролитного баланса у больных с хронической сердечной недостаточностью (ХСН)   и обычно развивается в результате мощных диуретических   эффектов петлевых диуретиков    (фуросемид, торсид и урегит). (1, 3)

При хранении хлопкового сырья большое значение имеет современное оборудование. В данной статье речь идет о современных технологиях, используемых на хлопкоочистительном заводе СП «Бек кластер», созданном в Мирзаабадском районе Сырдарьинской области, влиянии влаги на качество волокна при переработке хлопка.

Biz o‘pka эxinokokkozi bilan kasallangan  132 nafar bemorning (shulardan 86 nafari asoratlanmagan va 46 nafar asoratlangan o‘pka exinokokkozi bilan kasallangan bemorlar) jarrohlik davolash natijalari tahlilini taqdim etamiz. Shularning  118 (90,28%)  nafarida  operatsiyalar minimal invaziv yo‘l amalga  oshirildi. Asoratlanmagan o‘pka exinokokkoz bilan, operatsiya rejalashtirilgan 16 bemorni, faqat 14 (87,5%) nafarida troakar bilan qilingan teshiklar  orqali sof torakoskopik usulda exinokokkektomiya bajarish imkoni bo‘ldi. 61 holatda esa mini-kirishlar yordamida videotorakoskopik exinokokkektomiya amalga oshirildi. Kistalarning ikki tomonlama lokalizatsiyasi aniqlangan  7 (63,64%) nafar  bemorda bosqichma-bosqich operatsiya qilinib kistalar olib tashlandi, 3 ta (36,36%) holatda  esa - bir vaqtning o‘zida o‘pkadan exinokokkektomiya operatsiyasi bajarildi. Asosan,  bemorlarni 84 (97,67%) nafarida organlarni saqlovchi operatsiya bajarilib, o‘pkadagi qoldiq bo‘shliq tikib plastika qilishni  turli xil modifikatsiyalari orqali bartaraf etildi. 2 ta (1,52%)  holatda exinokokk kistasini o‘pka qirg‘oq qismida joylashuvi va pnevmotsirrozi bo‘lgan bemorlarda o‘pkani qirg‘oq qismini exinokokk kistasi bilan birga rezeksiya qilish opreratsiyasi bajarildi.

XXI asrning эng muhim yechimini topmagan muammolardan biri bu qandli diabetni asoratlarini davolash muammosidir. Qandli diabetning og‘ir asoratlaridan biri diabetik panja sindromidir va oyoqlarda uchraydigan gangrenalar 25-30% ni tashkil qiladi. Jahon sog‘liqni saqlash tashkilotining bergan ma’lumotiga asosan qandli diabet kasalligi nogironlikka olib kelishda birinchi va o‘lim sur’ati bo‘yicha uchinchi o‘rinni egallaydi. Shuning uchun ham XXI asrni qandli diabetning noinfeksion pandemiyasi deb atalmoqda. Qandli diabetda yumshoq to‘qimalarda va diabetik panja sindromida uchraydigan yiringli-nekrotik asoratlarini davolash klinik xirurgiyaning muhim muammolaridan biri bo‘lib qolmoqda. Tadqiqotimizda Samarqand shahar tibbiyot birlashmasining yiringli-septik bo‘limi va Samarqand Tibbiyot universitetining ko‘p tarmoqli klinikasining umumiy xirurgiya bazasida bo‘lgan yumshoq to‘qimalarning yiringli-nekrotik yallig‘lanish zararlanishi bilan qandli diabetga chalingan 86 nafar bemorning davolash natijalari ko‘rib chiqilgan.

Недифференцированная соединительная ткань обладает высокой способностью к регенерации и обновлению, что позволяет ей эффективно выполнять свои функции в организме. Благодаря этим свойствам, она играет важную роль в обеспечении и поддержании здоровья человека. В статье рассмотрены методы обследования, инструментальные и лабораторные исследования, а также возможные подходы к диагностике данного состояния. Учитывая сложность и многообразие симптомов НДСТ, предложены методы для выявления патологий соединительной ткани, связанных с этим расстройством.

История отоларингологии имеет длинные корни и прошла через значительное развитие в течение многих веков. В данной статье приведены данные об этапах развития и становления отоларингологии, о известных личностях и современных достижениях.

На фоне беременности ухудшается течение или впервые происходит манифестация большого круга хронических заболеваний органов и систем. Вследствие чего важно развивать отрасль акушерства на современном этапе. В статье рассматриваются инновационные методы и нововведения в области акушерства.

Статья рассматривает остроконечные респираторные вирусные инфекции (ОРВИ) как одну из наиболее распространенных групп заболеваний, поражающих дыхательные пути человека. Обсуждаются основные симптомы, лечение и профилактика ОРВИ, включая рекомендации по уходу за собой в период заболевания. Статья призвана повысить осведомленность читателей о проблеме ОРВИ и помочь им принимать эффективные меры для своего здоровья.