BOLALAR VA O'SMIRLARDA MIGRENDA GUMORAL IMMUNITETNING O'ZGARISHLARI
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Bolalar migreni, gumoral immunitet, immunoglobulin G, immunoglobulin M, aylanuvchi immun komplekslari, immun disbalans, auralik migren, immunopatogenez.Abstrak
Bolalar va o‘smirlardagi migren faqat nevrologik kasallik sifatida emas, balki immun tizimining ishtiroki bilan bog‘liq bo‘lgan holat sifatida ham tobora ko‘proq tan olinmoqda. Ushbu maqolada bolalar migrenining patogenezi va klinik ko‘rinishida gumoral immunitetning roli yoritilgan. 6 yoshdan 18 yoshgacha bo‘lgan 42 nafar bolada migrenning turli shakllari bo‘yicha o‘tkazilgan tadqiqotda immunoglobulinlar va aylanuvchi immun komplekslari (AIK) darajalarida sezilarli farqlar aniqlandi. Ma’lumotlarga ko‘ra, ayniqsa auralik migren bilan og‘rigan bolalarda immun tizimi disbalansi mavjud. Migrenning immunologik jihatlarini chuqur tushunish erta tashxis qo‘yish, prognozlash va shaxsiylashtirilgan davolash usullarini ishlab chiqishga xizmat qilishi mumkin.
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