СLINICAL AND LABORATORY EVALUATION OF OZONE THERAPY IN PREGNANT WOMEN WITH INFECTIOUS-INFLAMMATORY PLACENTAL DYSFUNCTION

Abstract:

Infectious-inflammatory placental dysfunction is one of the leading causes of complicated pregnancy, associated with impaired microcirculation, activation of systemic inflammatory response, and disturbances in the hemostatic system. These changes are reflected in laboratory abnormalities, including anemia, inflammatory markers, and hypercoagulation, which indicate the severity of the pathological process and dysfunction of the mother–placenta–fetus system. Standard treatment approaches do not always ensure sufficient correction of these disorders, which necessitates the search for more effective therapeutic strategies. Ozone therapy is considered a promising adjunct due to its anti-inflammatory, antihypoxic, and rheological effects.