Natural Sciences in the modern world: theoretical and practical research

Антикоагулянтная терапия играет важнейшую роль в профилактике и лечении тромботических заболеваний, таких как тромбофлебит, венозная тромбоэмболия и инсульты. Варфарин, как традиционный антикоагулянт, широко применяется на протяжении многих лет, но его использование связано с рядом ограничений. Регулярный лабораторный мониторинг, высокий риск лекарственных взаимодействий и необходимость строгого соблюдения диеты снижают удобство и безопасность его применения.

Toshkent shahrida reabilitatsiyaning uy bosqichida tashkil etish va muroja’atlarni tahlil qilish.

Открытые переломы конечностей представляют собой одну из самых сложных форм травматизма, сопровождающуюся высоким риском инфекционных осложнений и других патологических процессов. В статье представлен опыт комплексного подхода к лечению открытых переломов, включая оперативное вмешательство, наружную фиксацию, гипербарическую оксигенацию и антибактериальную терапию. В исследовании проанализированы 42 пациента, получивших травму в результате дорожно-транспортных происшествий. Применение предложенного комплекса мер позволило достичь положительных результатов в заживлении ран, минимизировать развитие инфекционных осложнений и ускорить восстановление пострадавших.

insultni oʻtkazgan bemorlarda reabilitatsiyani uy sharoitida olib borish va reabilitatsiya davomiyligiga natijalarning bogʻliqligini oʻrganish.

the article deals with new methodologies for teaching human anatomy using color photos of natural anatomical specimens. About the need for podgotovki for publication by anatomical atlases of a new type of photographic atlases of anatomical specimens, to establish banks of these photos and use them for demonstrations on monitors in the training of the anatomical rooms.

Кожные заболевания, такие как экзема, псориаз, дерматиты и другие воспалительные поражения кожи, являются одной из наиболее распространённых причин обращения к дерматологам. Эти заболевания не только вызывают физический дискомфорт, но и существенно снижают качество жизни пациентов. Часто такие состояния сопровождаются болью, зудом, воспалением, шелушением и другими косметическими дефектами, которые могут влиять на психологическое состояние больного, снижая его самооценку и социальную активность. Одним из таких подходов являются фитотерапевтические методы, которые включают использование лекарственных растений для лечения кожных заболеваний.

This scientific paper provides information about the biological description and chemical composition of Girgensohnia diptera Bunge.

Prostata saratoni dunyo bo‘ylab erkaklarda keng tarqalgan o‘smalardan biri bo‘lib, saraton bilan bog‘liq o‘lim holatlarining asosiy sabablaridan biridir. Kasallik dastlabki bosqichlarda simptomlarsiz kechishi mumkinligi sababli, uni erta aniqlashda profilaktik tekshiruvlar muhim rol o‘ynaydi. Ushbu tadqiqot prostata saratonini erta aniqlash usullarining samaradorligini baholaydi, jumladan prostata-spesifik antigen (PSA) testi, raqamli rektal tekshiruv (DRE) va ko‘p parametrli magnit-rezonans tomografiya (mpMRI) kabi zamonaviy tasvirlash usullari.

This article analyzes the possibilities for improving the accounting and analysis of international money transfers in banks. The effective management of international money transfers is crucial not only for increasing the liquidity and profitability of the banking system but also for enhancing the quality of services provided to customers and adapting to international financial requirements and standards. The article examines modern approaches to improving the accounting and analysis of international money transfers, their practical significance, and advantages. During the research, recommendations were developed for implementing digital technologies, utilizing automated accounting systems, enhancing transaction security, and applying international best practices. The results of this study can serve as practical support in optimizing money transfer processes, increasing operational efficiency, and developing international financial transactions in the banking system.

This study analyzed the practice of prescribing psychotropic drugs in several major American oncology centers. During the study period, a group of patients were hospitalized in oncology centers, and if we take them as a whole, i.e., 100%, then at least 51% were prescribed one psychotropic drug. The most frequently prescribed drugs were hypnotics, which accounted for 48% of the total prescriptions, followed by antipsychotics in 26%, and anti-anxiety drugs in 25%. Antidepressant drugs accounted for only 1% of psychotropic prescriptions. Analysis of the basics of prescriptions showed that 44% of psychotropic prescriptions were written for sleep, 25% were given for nausea and vomiting; about 17% were associated with depression, and 12% were associated with diagnostic medical procedures. The total prescription rate was approximately 2 psychotropic drugs per patient, only 2% of prescriptions were found to cause side effects.

This article provides information on the importance of leaf cress salad, its biological, morphological features and place in the world in terms of consumption, as well as the overall yield of vegetables.

Sportchilarning yuqori jismoniy faolligi ularning oshqozon-ichak tizimi salomatligiga bevosita ta’sir qiladi. Ushbu tadqiqotda sportchilarda keng tarqalgan oshqozon-ichak kasalliklari va ularni tashxislashning zamonaviy usullari tahlil qilindi. Tadqiqot natijalari ushbu kasalliklarning oldini olish va samarali davolash yo‘llarini aniqlashga xizmat qiladi.

Морфология как наука, изучающая форму и структуру живых организмов на разных уровнях организации, является основой для понимания биологических процессов и заболеваний. В последние десятилетия с развитием новых технологий и методов исследования, таких как молекулярная биология, геномика, электронная микроскопия и 3D-моделирование, морфология заново открывает для ученых важнейшие аспекты клеточной и тканевой архитектуры, их изменений в процессе развития и при различных патологических состояниях.

This thesis discusses the chronic and progressive disease of the nasal and paranasal sinuses, inflammation of the mucous membrane. It provides information on the causes and forms of chronic rhinosinusitis with polyps, damage to the nasal mucosa, measures and effective methods of treating the disease based on the analysis.

Positron physical-chemistry has been a significant area of scientific investigation in recent decades. However, low-energy positron scattering by atoms and molecules still presents several open questions, particularly regarding the effects of low-angle scattering on measured cross sections and the role of target polarization in the comparison between theoretical and experimental results. In this study, we examine low-energy positron collisions with H₂ molecules, focusing on the convergence of the polarization contribution in the scattering potential.

Otosclerosis is a pathological bone remodeling disorder affecting the middle and inner ear. The term derives from "oto," meaning ear, and "sclerosis," referring to abnormal hardening. Initially described by Antonio Maria Valsalva in 1735 and later characterized pathologically by Adam Politzer in 1839, otosclerosis involves the replacement of the normal dense endochondral bone of the otic capsule with irregular spongy bone, which eventually hardens and leads to fixation of the stapes footplate.

This study presents the results of a morphological examination of the liver in healthy elderly individuals to investigate the process of nucleolar granular component migration from the nucleus to the cytoplasm of hepatocytes. It was established that this process is analogous to that observed in animals, with no fundamental differences between species. The analysis revealed age-related morphological changes, such as lipofuscin accumulation, dystrophic processes, and nuclear polymorphism. Special attention was given to the characteristics of migrating nucleoli, including their shape, size, and potential mechanisms of exit from the nucleus into the cytoplasm. The obtained data confirm the possibility of nucleolar migration in humans and its potential role in cellular processes.

Koʻhna ark - Xivaning qadimiy qal’asi bo‘lib, “Ichon qal’a”dagi xon saroylaridan biridir. Qal’aning paydo bo‘lish tarixi Xiva shahri tarixi bilan chambarchas bog‘liqdir. Xivadagi ushbu meʼmoriy yodgorlik majmuasi XVII asrdan XIX asr o‘rtalarigacha bo‘lgan davr oralig‘ida barpo etilgan. Ichan qalaning gʻarbiy qismida joylashgan. Koʻhna Arkdagi binolar, asosan XVII asrda Anoʻshaxonning oʻgʻli Arangxon davrida usta, shoir Mavlono Vafoiy tomonidan qurilgan. 1804-1806 yillarda qayta tiklab taʼmir etilgan. Koʻhna Ark toʻrt hovliga boʻlinib, atrofi baland paxsa devor bilan oʻralgan. Sharq tomondagi darvozadan oʻng tomondagi yoʻlakka oʻtilib, u orqali saroy masjidi va xonning zarbxonasiga boriladi. Haramxona arkning shimolida, koʻrinishxona gʻarbiy qismida, oʻrtasida Oq shayx bobo koʻshki joylashgan. Darvozaning chap tomonida xonning xizmatkorlari yashaydigan xonalar, omborxona va otxonalar boʻlgan.

This article discusses the use of medicinal dandelion (field dandelion) for the treatment of humans and animals, the prevention of diseases, as well as in the food, perfumery and cosmetic industries. It presents the results of a study on the origin, geographical distribution and bioecology of the medicinal dandelion or field dandelion species.

Водоросли — внетаксономическая группа, включающая несколько отделов и насчитывающая более 100 тыс. видов. Водоросли называют также низшими растениями, так как им не свойственно разделение тела на ткани и органы.

В данной статье описаны результаты научных исследований проведенных с целью биотехнологической системы является культивирование водных растений (Azolla caroliniana, Lemna minor L.) на сточных водах в целях их биологической очистки с одновременным получением кормовой биомассы.

Heart failure is a widespread condition among adults, contributing significantly to global morbidity and mortality. Its principal risk factors include coronary artery disease, hypertension, obesity, diabetes mellitus, chronic pulmonary disorders, a family history of cardiovascular disease, and cardiotoxic treatments. A key contributor to poor outcomes in heart failure patients is the ongoing progression of the disease. This review examines the evidence regarding both established and emerging neurohumoral biomarkers for managing and diagnosing heart failure progression. Although numerous biomarkers have been suggested as potentially useful, none yet embody the ideal characteristics needed for effective screening, diagnosis, prognosis, and therapeutic management. Furthermore, the clinical and pathophysiological importance of these biomarkers may vary according to the disease's presentation, stage, and severity. We also discuss the primary classifications of heart failure based on left ventricular ejection fraction—including heart failure with preserved ejection fraction, heart failure with reduced ejection fraction, and the newly defined heart failure with mid-range ejection fraction. Specific biomarker panels may offer varying predictive performance for the progression of heart failure, particularly in forecasting the future course of the disease and in monitoring adverse or reverse left ventricular remodeling. This article aims to provide an overview of both the fundamental and additional mechanisms underlying heart failure progression, contributing to a more comprehensive understanding of its pathogenesis.

Препарат Биокор представляет собой комплекс иминопроизводного госсипола с N – поливинилпирролидоном. Применяется в качестве противоопухолевое средство [1].

The most prevalent form of nutritional deficiency resulting in anemia is iron deficiency, primarily caused by insufficient consumption of dietary iron. World Health Organizations’ information indicate that, 40% of all children aged 6–59 months, 37% of pregnant women and 30% of women 15–49 years of age are suffer from anaemia. Anemia is most commonly found in children under the age of 5, especially infants and those under 2 years old. These young children are particularly vulnerable to developing anemia [1].

Ushbu maqola, ona-yo'ldosh kompleksi zararlanishi natijasida yuzaga keladigan homila ichi gipoksiyasining rivojlanish mexanizmlarini va uning homila yurak-qon tomir tizimiga ta’sirini o’rganishga qaratilgan. Maqolada 2020-2025 yillar orasida nashr etilgan ilmiy adabiyotlar tahlil qilingan va gipoksiya, gipoksemiya, stressga qarshi gormonlar va homiladorlikda yurak-qon tomir kasalliklari kabi muhim kalit so'zlar asosida tahlil yasalgan. Homila ichi gipoksiyasining turli bosqichlari (gipoksemiya, gipoksiya, asidemiya) va uning homilaning rivojlanishiga ta’siri ko’rib chiqildi. Maqolada homiladagi qon tomir tizimi va stressga qarshi gormonlar faollashuvi gipoksiyaning boshlanishiga qanday ta’sir ko'rsatishini ko'rsatgan. Homila rivojlanishiga zarar yetkazishi mumkin bo‘lgan omillar, shu jumladan ona-yo'ldosh kompleksi zararlanishi, onadagi yurak-qon tomir kasalliklari va gemolitik kasalliklar ko'rib chiqildi.

Актуальность исследования современных подходов к оценке состояния рубца на матке после кесарева сечения обусловлена ростом числа оперативных родоразрешений и связанными с этим рисками для последующих беременностей. Несостоятельность рубца может привести к серьезным осложнениям, таким как разрыв матки, плацентарные аномалии и бесплодие, что требует разработки более точных диагностических методов. Современные технологии, включая 3D-ультразвуковое исследование, эластографию и МРТ, позволяют более объективно оценивать структуру и функциональную состоятельность рубца, что способствует выбору оптимальной тактики ведения беременности и снижению материнской и перинатальной заболеваемости.

Baliqchilikda baliqlarning stress darajasini o'rganish, ularning o'sishi, rivojlanishi va sog'lig'ini saqlash uchun muhimdir. Baliqlardagi stress omillari va ularga qarshi kurashda adaptogenlar rolini aniqlash, baliqchilik sanoatini rivojlantirish uchun muhim ahamiyatga ega.

Matn va grafik muharrirlari bo‘limini o‘qitish metodikasi matnni yaratish, tahrirlash va grafikalashtirish bo‘yicha o‘quvchilarga keng qamrovli bilim va ko‘nikmalar beradi. O‘quvchilar matn muharrirlaridan (Microsoft Word, Google Docs) va grafik muharrirlaridan (Adobe Photoshop, Illustrator, Canva) samarali foydalanishni o‘rganadilar. Ushbu metodika, matnni tahrirlash, tasvirlarni yaratish va dizayn elementlarini qo‘llashni o‘rgatish orqali o‘quvchilarda kreativ fikrlash va vizual kommunikatsiya ko‘nikmalarini rivojlantiradi. Matn va grafik muharrirlaridan foydalangan holda o‘quvchilar maketlar, infografikalar, reklama bannerlari, taqdimotlar, va boshqa vizual materiallar yaratadilar. Metodika o‘quvchilarga dizayn va matn yaratishda vizual va estetik tamoyillarni o‘rgatish bilan birga, grafikalarning ma’lumotlarni samarali taqdim etishda qanday rol o‘ynashini tushunishga yordam beradi.

Ushbu maqolada iqlim o`zgarishi va uning O`zbekistonga, jumladan Qo`qon vohasi va uning landshaftlariga ta`siri tahlil qilingan. Qo`qon vohasi va uning tabiiy geografik joylashuvi, iqlimini shakllantiruvchi asosiy omillari yoritilgan. Iqlim o`zgarishi sharoitida landshaftlar barqarorligini ta`minlash to`g`risida fikr mulohazalar yoritilgan.

Любой патологический процесс, в том числе при вирусном гепатите С, сопровождается повышенным образованием свободных радикалов и  связанное с этим усиление процессов пероксидации липидов, что сопровождается нарушением свойств биологических мембран и нарушением функционирования клеток. Основную функцию защиты при активации процессов липопероксидации выполняет антиоксидантная система клеток, недостаточность которой становится одним из факторов активации прооксидантных реакций в организме.