HISTOLOGICAL EVALUATION OF SALIVARY GLAND ALTERATIONS IN AUTOIMMUNE DISEASES.
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Abstrak:
Histological assessment of salivary gland alterations in autoimmune disorders highlights the profound structural and cellular changes occurring within glandular tissues, particularly in Sjögren’s syndrome (SS). This chronic autoimmune disease primarily targets the exocrine glands, resulting in lymphocytic infiltration, progressive inflammation, and functional impairment, which clinically manifest as xerostomia (dry mouth) and xerophthalmia (dry eyes).
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Daniels TE. Labial salivary gland biopsy in Sjögren’s syndrome: assessment as a diagnostic criterion in 362 suspected cases. Arthritis Rheum. 1984;27(2):147–56.
Fox RI. Sjögren’s syndrome. Lancet. 2005;366(9482):321–31.
Jonsson R, Vogelsang P, Volchenkov R, Espinosa A, Wahren-Herlenius M, Appel S. The complexity of Sjögren’s syndrome: Novel aspects on pathogenesis. Immunol Lett. 2011;141(1):1–9.
Risselada AP, Looije MF, Kruize AA, Bijlsma JW, van Roon JA. The role of ectopic germinal centers in the immunopathology of Sjögren’s syndrome: Implications for therapy. Autoimmun Rev. 2013;12(9):912–20.
Vitali C, Bombardieri S, Jonsson R, Moutsopoulos HM, Alexander EL, Carsons SE, et al. Classification criteria for Sjögren’s syndrome: a revised version of the European criteria proposed by the American-European Consensus Group. Ann Rheum Dis. 2002;61(6):554–8.
Baer AN, McAdams DeMarco MA, Shiboski SC, Lam MY, Challacombe S, Daniels TE, et al. The SSB-positive/SSA-negative antibody profile is not associated with key phenotypic features of Sjögren’s syndrome. Ann Rheum Dis. 2015;74(8):1557–61.
Tzioufas AG, Kapsogeorgou EK, Moutsopoulos HM. Pathogenesis of Sjögren’s syndrome: what we know and what we should learn. J Autoimmun. 2012;39(1–2):4–8.
Sene D. Small vessel vasculitis in Sjögren’s syndrome: clinical and therapeutic aspects. Autoimmun Rev. 2017;16(5):456–64.