DISEASES OF THE SALIVARY GLANDS WITH DAMAGE TO THE THYROID GLAND
Main Article Content
Abstract:
In this article, morphofunctional changes observed in the salivary glands during thyroid dysfunction, their clinical course, and pathogenetic mechanisms were scientifically analyzed. During the study, disorders of saliva secretion against the background of hypothyroidism and hyperthyroidism, dystrophic changes in the tubular epithelium, fibrous processes in the parenchyma of the salivary glands, and microangiopathic lesions were noted, which led to a decrease in the protective function of the oral cavity and the development of such diseases as xerostomia, sialoadenitis, and sialoangioektazia. Clinical observations showed that in patients with thyroid diseases, salivary gland dysfunction occurs in 62-78% of cases, with a sharp decrease in secretion in hypothyroidism and an increase in inflammatory processes in hyperthyroidism. The article also emphasized the importance of an integrated approach to ultrasound, sialometry, and hormonal tests in diagnosis. As a rehabilitation approach, the normalization of the endocrine state, physiotherapeutic procedures, antioxidant therapy, and gland-stimulating methods were recognized as effective. The research results confirm the need for early detection and complex treatment of salivary gland dysfunction associated with thyroid diseases.
Article Details
How to Cite:
References:
Burgess, J. (2019). Thyroid hormone regulation and its impact on salivary gland physiology. Journal of Endocrine Research, 45(3), 210–218.
Khan, M. A. (2020). Hyperthyroidism-induced morphological changes in salivary glands: A clinical overview. International Journal of Oral Biology, 12(2), 55–63.
Martins, L. F., Costa, R. P., & Almeida, J. R. (2021). Hypothyroidism and salivary gland dysfunction: Functional and structural alterations. Oral Medicine & Biology, 17(4), 301–309.
Ribeiro, A. S. (2018). Xerostomia and metabolic disorders: Oral manifestations of endocrine diseases. Clinical Oral Science Review, 9(1), 44–52.
Silva, T. R. (2022). Autoimmune thyroiditis and lymphocytic infiltration of salivary glands: Comparative morphological analysis. Journal of Immunopathology and Oral Health, 28(1), 72–81.
Kamilova, I. A., Pakhomova, J. E., & Nadjmutdinova, D. K. (2020). Analysis of the role of 1G/2G polymorphism in the MMP1 gene in the development and clinical course of cervical intraepithelial neoplasia. European Journal of Molecular and Clinical Medicine, 7(2), 850-859.

