KARDIOXIRURGIK SHAROITDA PULSATIK VA NOPULSATIK PERFUZIYANING MIYA, BUYRAK VA MIOKARD PERFUZIYASIGA TA’SIRI
Article Sidebar
Main Article Content
Аннотация:
Kardioxirurgik jarayonlarda organlarning yetarli perfuziyasi bemor natijalari va jarrohlikdan keyingi asoratlar xavfi bilan bevosita bog‘liq. Pulsatik va nopulsatik perfuziya modellarining miyaga, buyraklarga va miokardga ta’siri klinik amaliyotda muhim mavzudir. Pulsatik perfuziya fiziologik ritmga yaqin qon oqimi orqali organlarga kislorod va oziq moddalar yetkazilishini optimallashtiradi, endotelial va miokard funktsiyasini qo‘llab-quvvatlaydi. Nopulsatik perfuziya esa doimiy qon oqimi bilan xarakterlanadi, ba’zi hollarda qisqa muddatli barqarorlikni ta’minlasa-da, uzoq muddatli perfuziyada organlarda regional qon yetishmovchiligi yuzaga kelishi mumkin. Eksperimental va klinik tadqiqotlar shuni ko‘rsatadiki, pulsatik perfuziya miyadagi oksigen yetkazilishini yaxshilaydi, postoperativ kognitiv disfunktsiya xavfini kamaytiradi va buyrak funksiyasini saqlashga yordam beradi. Miokard perfuziyasi uchun pulsatik qon oqimi kislorod yetkazilishini optimallashtiradi, ishemiya va reperfuziya jarayonlaridagi shikastlanish xavfini kamaytiradi. Shu bilan birga, perfuziya strategiyasini tanlashda individual bemor xususiyatlari, jarrohlik davomiyligi va komorbid kasalliklar hisobga olinishi muhimdir.
Article Details
Как цитировать:
Библиографические ссылки:
Kirklin J.K., Barratt-Boyes B.G. Cardiac Surgery. – 4th ed. – Philadelphia: Elsevier Saunders, 2013.
Gravlee G.P., Davis R.F., Kurusz M., Utley J.R. Cardiopulmonary Bypass: Principles and Practice. – 3rd ed. – Philadelphia: Lippincott Williams & Wilkins, 2008.
Edmunds L.H. Extracorporeal Circulation for Cardiac Surgery. – Oxford: Blackwell Scientific Publications, 1996.
Likosky D.S., Marrin C.A., Caplan L.R. et al. Determination of cerebral blood flow during pulsatile and nonpulsatile cardiopulmonary bypass // Annals of Thoracic Surgery. – 2003. – Vol. 75. – P. 140–145.
Ji B., Undar A. An update on pulsatile cardiopulmonary bypass // Journal of Extra-Corporeal Technology. – 2006. – Vol. 38. – P. 152–160.
Murkin J.M. Cerebral autoregulation and cardiopulmonary bypass // Journal of Cardiothoracic and Vascular Anesthesia. – 2007. – Vol. 21. – P. 812–818.
Angelini G.D., Taylor F.C., Reeves B.C. Early and midterm outcome after pulsatile and nonpulsatile cardiopulmonary bypass // Annals of Thoracic Surgery. – 1999. – Vol. 67. – P. 414–418.
Licker M., Diaper J., Villiger Y. et al. Impact of cardiopulmonary bypass on renal function // European Journal of Anaesthesiology. – 2014. – Vol. 31. – P. 517–526.
Braunwald E. Heart Disease: A Textbook of Cardiovascular Medicine. – 11th ed. – Philadelphia: Elsevier, 2019.
Bojar R.M. Manual of Perioperative Care in Adult Cardiac Surgery. – 5th ed. – Oxford: Wiley-Blackwell, 2011.