COVID-19 ЎТКАЗГАН КОМОРБИД ҲОЛАТДАГИ БЕМОРЛАРДА СУРУНКАЛИ БУЙРАК КАСАЛЛИГИНИНГ КЕЧИШИНИ БАҲОЛАШ
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Abstrak:
Буйрак касалланганда нефроннинг турли қисмларида ACЕ2 нинг юқори даражада ишлаб чиқарилиши , SARS-CoV‑2 нинг юқишига имкон берувчи хавф омилидир. Полимераза занжири реакцияси (ПЗР) ёрдамида COVID‑19 билан касалланган беморларнинг сийдикида коронавирус зарралари аниқланади. Хусусан, SARS-CoV‑2 хўжайин ҳужайраларига кириш учун ACЕ2 дан фойдаланади. Маълумки, буйраклардаги ангиотензинни ўзгартирувчи 2-турдаги фермент (ACЕ2) учун рецепторлари сони нафас олиш органларига (ўпка) қараганда деярли 100 баравар кўп. Бу эса ўз навбатида, буйракалар зарарланиш эҳтимолини янада оширади.
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COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup / M. K. Nadim [et al.] // Nat. Rev. Nephrol. – 2020 Dec. – Vol. 16. – P. 747–764.
COVID-19 and Older Adults: What We Know / Z. Shahid [et al.] // J. Am. Geriatr. Soc. – 2020 May. – Vol. 68, N 5. – P. 926–929.
Comorbid Chronic Diseases and Acute Organ Injuries Are Strongly Correlated with Disease Severity and Mortality among COVID-19 Patients: A Systemic Review and Meta- Analysis / X. Wang [et al.] // Research (Wash D C). – 2020 Apr. – Vol. 2020. – 2020:2402961.
Henry, B. M. Chronic kidney disease is associated with severe coronavirus disease 2019 (COVID-19) infection / B. M. Henry, G. Lippi // Int. Urol. Nephrol. – 2020. – Vol. 52, N 6.– P. 1193–1194.
International Society of Nephrology (ISN) [Electronic resource]. – Mode of access: https://www.theisn.org/covid-19.– Date of access: 22.01.2021.
Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area / S. Richardson [et al.] // JAMA. – 2020 May. – Vol. 323, N 20. – P. 2052–2059.
Acute kidney injury in SARS-CoV-2 infected patients / V. Fanelli [et al.] // Crit. Care. – 2020 Apr. – Vol. 24, N 1. – P. 155. Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection / X. Zou [et al.] // Front Med. – 2020 Apr. – Vol. 14, N 2. – P. 185–192.
COVID-19: A Multidisciplinary Review / N. Chams [et al.] // Front. Public. Health. – 2020 Jul. – Vol. 8. – P. 383.
Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg9 bradykinin/BKB1R axis and facilitates LPS- induced neutrophil infiltration / C. P. Sodhi [et al.] // Am. J. Physiol. Lung. Cell. Mol. Physiol. – 2018 Jan. – Vol. 314, N 1. – P. L17–L31.
Angiotensin II induces kidney inflammatory injury and fibrosis through binding to yeloid differentiation protein-2 (MD2) / Z. Xu [et al.] // Sci. Rep. – 2017 Mar. – Vol. 7. – 44911.