THE IMPORTANCE OF THE ENDOMETRIAL LAYER IN PREVENTING OF FAILURE IN VITRO FERTIZILATION

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Выпуск: Том 2 № 27 : Наука и инновация
Раздел: Статьи
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Obstetrician-gynecologist at Republican Specialized Scientific and Practical Medical Center for Mother and Child Health of Fergana Branch
info@in-academy.uz

Аннотация:

In assisted reproductive technology (ART) programs, 60–70% of women fail to become pregnant after embryo transfer. Repeated implantation failure (RIF) remains a black box in daily practice due to the complicated categorization and causes of this physio-pathological dysregulation. Different causes of RIF were reported, mainly multifactorial, endometrial and idiopathic. Multifactorial RIF can be caused by maternal and paternal factors, gamete and embryo quality, infections and lifestyle changes in combination with psychological status and oxidative stress. Impaired endometrium function such as abnormal growth or loss of vascularization can account for endometrial RIF, but idiopathic RIF, caused mainly by abnormal cross-talk between the embryo and endometrium, remains the principal question and needs to be elucidated.

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Abdujapparova, N. . (2024). THE IMPORTANCE OF THE ENDOMETRIAL LAYER IN PREVENTING OF FAILURE IN VITRO FERTIZILATION. Наука и инновация, 2(27), 53–58. извлечено от https://in-academy.uz/index.php/si/article/view/37589

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