GEM BIOSINTEZI STIMULYATORLARI ORQALI YURAK YETISHMOVCHILIGINING KORREKSIYASI

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Issue: Vol. 4 No. 6 : Innovative research in the modern world: theory and practice
Section: Articles
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Toshkent Tibbiyot Akademiyasi 1-davolash fakulteti 202-guruh
info@in-academy.uz

Abstract:

Yurak yetishmovchiligi (YY)  sog‘liqni saqlash muammolaridan biri bo‘lib, uning kelib chiqishi oksidlovchi stress, metabolik disbalans va energiya yetishmovchiligi sabab bo’ladi. Gem biosintezi yurak mushak hujayralarida kislorod tashish, energetik metabolism, oksidlanish-fosforillanishni ta’minlashda asosiy ahamiyatga ega. Gem biosintezining buzilishi mitoxondriyal disfunksiya va ATP ishlab chiqarishning pasayishiga olib keladi va bu orqali YY rivojlanishini tezlashtiradi. Shuning uchun, gem biosintezini stimulyatsiya qiluvchi farmakologik vositalarni qo‘llash YY farmakoterapiyasida istiqbolli yo‘nalishlardan biri hisoblanadi.

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How to Cite:

Shuxratov, A. . (2025). GEM BIOSINTEZI STIMULYATORLARI ORQALI YURAK YETISHMOVCHILIGINING KORREKSIYASI. Innovative Research in the Modern World: Theory and Practice, 4(6), 32–33. Retrieved from https://in-academy.uz/index.php/zdit/article/view/45373

References:

Smith, A. G., & Karp, J. (2019). Heme biosynthesis and its disorders. Journal of Molecular Medicine, 97(5), 567-580.

Anderson, K. E., & Desnick, R. J. (2020). Heme biosynthetic pathway and mitochondrial function in cardiovascular disease. Cardiology Reviews, 28(3), 151-162.

Johnson, M. K., & Freeman, D. A. (2018). Iron metabolism and heme synthesis in cardiac health and disease. Circulation Research, 122(4), 515-529.

Brown, R. S., & Taylor, J. M. (2021). Pharmacological approaches to modulating heme biosynthesis in heart failure. European Journal of Pharmacology, 899, 173972.

Miller, C. L., & Lewis, D. R. (2022). Oxidative stress and its impact on heme metabolism in cardiomyocytes. Frontiers in Physiology, 13, 856923.