O'SMIRLARDA SURUNKALI BUYRAK KASALLIGINING ERTA XAVF OMILLARINI ANIQLASH
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Abstrak:
Adabiyotlar tahlili shuni ko'rsatadiki, surunkali buyrak kasalliklari (SBK) bo'lgan o'smirlar soni har yili ortib bormoqda. Bugungi kunda yigirmadan ortiq buyrak kasalliklarining oxirgi klinik ko’rinishi SBK sifatida namoyon bo’lishi ma'lum. So'nggi yillardagi tadqiqotlar shuni ko'rsatadiki, SBK rivojlanishi va progressiyasida buyrak va siydik yo'llarining tug'ma anomaliyalari, kam vaznda tug’ilish, chala tug’ilish, arterial gipertenziya, erkak jinsi, kaltsiy va fosfor almashinuvining metabolik kasalliklari, nefrotoksik dorilarni qo'llash va boshqalar yetakchi rolni o’ynaydi. Ayniqsa perinatal davrdagi o’zgarishlar buyrak nefronlarining rivojlanishiga to’sqinlik qilib, ushbu kasallikning yanada tez suratda progressiyasiga olib keladi
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