O‘TKIR MIOLABLASTIK LEYKOZLARNING MOLEKULYAR-GENETIK XUSUSIYATLARI

Main Article Content

Аннотация:

Ushbu maqolada o‘tkir mioloblastik leykoz (OML)ning molekulyar-genetik xususiyatlari tahlil qilingan. Leykoz hujayralarida uchraydigan asosiy genetik o‘zgarishlar, ularning patogenezdagi roli va klinik ahamiyati ko‘rib chiqilgan. Molekulyar belgilarning diagnostika, davolash strategiyasi va prognoz aniqlashdagi o‘rni yoritilgan. Shu bilan birga, zamonaviy genetik testlar va ularning individual yondashuvni shakllantirishdagi ahamiyati ham muhokama qilingan.

Article Details

Как цитировать:

Azimov , J., Dolliyev , A. ., & Xaqqulova , M. . (2025). O‘TKIR MIOLABLASTIK LEYKOZLARNING MOLEKULYAR-GENETIK XUSUSIYATLARI. Наука и инновация, 3(15), 117–118. извлечено от https://in-academy.uz/index.php/si/article/view/51878

Библиографические ссылки:

Döhner, H., Weisdorf, D. J., & Bloomfield, C. D. (2015). Acute Myeloid Leukemia. The New England Journal of Medicine, 373(12), 1136-1152. https://doi.org/10.1056/NEJMra1406184

Papaemmanuil, E., Gerstung, M., Bullinger, L., et al. (2016). Genomic Classification and Prognosis in Acute Myeloid Leukemia. The New England Journal of Medicine, 374(23), 2209-2221. https://doi.org/10.1056/NEJMoa1516192

Pollyea, D. A., Gutman, J. A., Gore, L., Smith, C. A., & Jordan, C. T. (2016). Targeting acute myeloid leukemia with venetoclax and hypomethylating agents. Blood Advances, 2(15), 1837–1842. https://doi.org/10.1182/bloodadvances.2016002743

Papaemmanuil, E., Gerstung, M., Bullinger, L., et al. (2016). Molecular landscape of acute myeloid leukemia. Nature, 538, 380–384. https://doi.org/10.1038/nature20592

Shah, A. A., & Steinhardt, G. (2019). Molecular Genetics of Acute Myeloid Leukemia. In Hematology: Basic Principles and Practice (7th ed., pp. 1035-1050). Elsevier.