STAPHYLOCOCCUS AUREUS (MRSA) INFEKSIYALARI: TARQALISH, VIRULENTLIK OMILLARI VA DAVOLASH MUAMMOLARI
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Staphylococcus aureus, xususan metitsillin-rezistent S. aureus (MRSA) turlarining infeksiyalari global sog‘liqni saqlash tizimi uchun jiddiy xavf hisoblanadi. MRSA infektsiyalari nafaqat hamshiralik va shifoxona muhitida tarqaladi, balki jamiyat ichida ham sezilarli darajada uchraydi, bu esa davolashni murakkablashtiradi va antibiotik qarshilikning keng tarqalishiga olib keladi. Infeksiyaning virulentlik omillari orasida toksinlar, biofilm hosil qilish qobiliyati, adhesinlar va immuntizimga qarshi mexanizmlar muhim rol o‘ynaydi. MRSA infektsiyalari teri va yumshoq to‘qima infektsiyalari, pnevmoniya, sepsis va endokardit kabi jiddiy klinik ko‘rinishlarga sabab bo‘lishi mumkin. Davolash muammolari antibiotik qarshilik darajasi yuqori bo‘lgani sababli cheklangan dorivor imkoniyatlar, dozalash murakkabligi va bemorning umumiy holati bilan bog‘liq. Maqolada MRSA infektsiyalarining epidemiologiyasi, virulentlik mexanizmlari, klinik ko‘rinishlari, diagnostik yondashuvlar va zamonaviy davolash strategiyalari ilmiy asoslangan tarzda tahlil qilinadi. Shuningdek, infeksiya tarqalishini oldini olish va antibiotik qarshilikni kamaytirishga qaratilgan profilaktik va nazorat choralari ham muhokama qilinadi.
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