BOLALARDA TEMIR TANQISLIGI ANEMIYASI: PREPARATLAR TANLOVI VA DOZALASH REJIMI
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Аннотация:
Bolalarda temir tanqisligi anemiyasi (TTA) — eng ko‘p uchraydigan gematologik kasalliklardan biri bo‘lib, u organizmda temir moddalarining yetarli miqdorda mavjud emasligi natijasida hemoglobin sintezining buzilishi va eritrositlar parametrlarining pasayishi bilan tavsiflanadi. Ushbu holat bolalarning o‘sish va rivojlanish sur’atlariga, immun tizim faoliyatiga, kognitiv funksiyalariga va umumiy sog‘lig‘iga sezilarli ta’sir ko‘rsatadi. TTA etiologiyasi odatda temir yetishmovchiligi bilan bog‘liq bo‘lsa-da, kasallikning rivojlanishida ovqatlanish yetishmovchiligi, gastroenterologik patologiyalar, qon yo‘qotish va genetik omillar ham muhim rol o‘ynaydi. Maqolada bolalarda TTAni davolashda qo‘llaniladigan preparatlar, ularning farmakologik xususiyatlari, dozalanish rejimi va individual yondashuv asoslari ko‘rib chiqilgan. Davolash strategiyasi temir preparatining farmakokinetik va farmakodinamik xususiyatlarini, bolaning yoshini, tana massasini, temir yetishmovchiligi darajasini va mavjud komorbid holatlarni hisobga olgan holda shakllantiriladi. Og‘iz orqali beriladigan temir preparatlari (ferro-sulfat, ferro-fumarat, ferro-glukonat) eng ko‘p qo‘llaniladigan vositalardir.
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