Eurasian Journal of Medical and Natural Sciences

Opiatga qaramlikni xronizatsiya qilish, alkogolizmga qo'shilish yoki aylantirish bo'yicha statistika umidsizlikka uchraydi. Affektiv buzilishlar giyohvandlikning barcha bosqichlarida majburiy ravishda mavjud bo'lib, chekinishdan keyingi sindrom bosqichida opioidlarga patologik jalb qilish doirasida bemorlarning faol behushlikka qaytishiga, kursni yomonlashishiga va remissiyani kamaytirishga olib keladi.

Tadqiqotchilar giyohvand moddalarni suiiste'mol qilishning qo'shma shakllari bo'lgan odamlar uchun ruhiy kasallikning boshlanishi va rivojlanishini belgilaydigan omillarning yaqin bog'liqligini ta'kidlaydilar. Alkogolizm va ruhiy kasalliklarning qo'shma kursi diagnostika, adekvat davolash, klinik tekshiruvda xususiyatlarga ega, chunki ikkita mutaxassislikning birlashmasida ko'rib chiqiladi.

This article substantiates the methodological conditions for enhancing the cognitive activity of students, in addition to the system of tasks using an interactive whiteboard, first of all, it includes methodological support that equips the teacher with knowledge in the field of the subject being studied and makes the lessons more interesting and information-filled.

Global modernizatsiya, sanoatlashish, urbanizatsiya va boshqa bir qator antropogen harakatlar atrof-muhitga nisbatan ifloslantiruvchi moddalarning salbiy taʼsirini oshiradi. Ulardan chiqqan chiqindilarni utilizatsiya qilish jarayonida, atmosfera, suv va tuproqqa jiddiy salbiy taʼsir ko‘rsatishi mumkin bo‘lgan og‘ir metallar va chiqindilar chiqishiga sabab boʼladi.

In this article entitled technology for obtaining a dry extract of a achillea filipendulina the process of obtaining a dry extract from the aerial parts of these plants is presented In experiments, the effect of extraction time and frequency, process temperature, hydromodule and degree of spray grinding on the yield of flavanoids and extractives was studied. The technological properties of the composite dry extract were also studied, the optimal composition was selected and the technology for the tablet dosage form was developed.

Ushbu maqolada Qashqadaryo viloyatining och tusli bо‘z tuproqlari sharoitida mineral о‘g‘itlar meyorlari va nisbatlarining oziqabop kuzgi bug‘doyning kuzgi о‘suv davrida quruq modda, tuplash bо‘g‘inida shakar tо‘plashiga ta’siri bо‘yicha olingan ilmiy ma’lumotlar tahlili keltirilgan.

Изучения состояния кожи и ее придатков у пациентов с гнездной алопецией на сегодняшний день считается одной из актуальных проблем в современной медицине. Существует множество факторов, приводящих к развитию данного заболевания. Однако изменение микроэлементного состава считается одной из основных гипотез в возникновении ГА. В данной статье приведена краткая информация о недостаточности некоторых микроэлементов, как возможных причинах развития ГА.

Ushbu maqolada Qoraqalpog'iston Respublikasida mahalliy tariq ekinlarining muhim roli o'rganiladi. Unda tariq yetishtirishning mintaqa qishloq xo‘jaligi, iqtisodiyoti va madaniy merosi uchun ahamiyati bayon etilgan. Mualliflarning ta’kidlashicha, tariq yetishtirish nafaqat oziq-ovqat xavfsizligi va iqtisodiy taraqqiyotni ta’minlaydi, balki boy madaniy merosning bir qismini tashkil etadi. Maqolada tariq yetishtirishning an’anaviy usullari va ularning Qoraqalpog‘iston Respublikasi barqarorligi va farovonligiga ta’siri ham ko‘rib chiqiladi.

Изучение маркеров апоптоза, пролиферации и ангиогенеза дает ценную информацию об осо­бенностях клинического течения опухолей, их прогноза, о скорости роста, лекарственной чувстви­тельности, об эффективности лечения, о выживаемости больных. Исследование молекулярных механизмов запрограммированной гибели клетки стало в последние годы одной из самых актуаль­ных проблем, что регистрируется при определении экспрессии молекулярно-биологических мар­керов Кi67, CD34, VGFR и p53. Экспрессия р53 играет важную роль в развитии агрессивности рака. В практическом плане уровень экспрессии мутантного р53 может быть прогностическим призна­ком.

В статье анализируется количественная корреляция между социально-демографическими факторами, такими как трудовой статус, возраст и семейное положение, и риском развития ишемической болезни сердца (ИБС). Исследования показывают, что статус работы, особенно высокий уровень стресса на рабочем месте, может быть связан с повышенным риском развития ИБС. Возраст является важным фактором, поскольку ИБС чаще всего диагностируется у пожилых людей. По данному показателю выявлена ​​восходящая тенденция: риск развития ИБС увеличивается с возрастом. Семейное положение также влияет на заболеваемость ИБС. Устойчивое семейное положение может быть защитным фактором против ИБС благодаря сети социальной поддержки. Однако в случае несчастливого брака или отсутствия партнера риск развития ИБС может возрасти. Результаты этой статьи подтверждают необходимость учитывать социально-демографические факторы при определении стратегий профилактики и контроля ИБС.

Savag‘ichlar pichoqsimon tayyorlanganida mosh donini dukkaklaridan ajratib dastlabki tozalash texnologik jarayoni talab darajasidaamalga oshiriladi va 98,5 foizni tashkil etib, shikastlanish darajasining eng kam bo‘lishi, don tozaligi yuqori va nobudgarchiligi kam bo‘lishi ta’minlanadi.

Ushbu maqola metabolik sindrom bilan bog'liq xavf omillarini har tomonlama ko'rib chiqishni, ularning ta'sirini tahlil qilish uchun mavjud adabiyotlarga asoslanishni ta'minlaydi. Tadqiqot semirish, insulin qarshiligi, gipertoniya, dislipidemiya, harakatsiz turmush tarzi, genetika va ovqatlanish odatlari kabi turli omillarni o'rganadi. Shuningdek, ushbu xavf omillarining oldini olish va boshqarish uchun oqibatlari muhokama qilinadi

Trauma is a leading cause of death globally, disrupting immune system balance and potentially causing infections and inflammatory issues. A major challenge is preventing multiple organ dysfunction syndrome (MODS) due to septic complications following severe trauma. Typically, after a severe injury, the immune system shifts from a pro-inflammatory to a counter-inflammatory state, which is seen as a protective response to balance the innate and adaptive immune systems. Our research shows that injury activates inflammasomes and primes Toll-like receptors, enhancing the innate immune system’s antimicrobial defense. However, trauma can also cause a "two-hit" response. Additionally, we found that injury increases regulatory T cell activity, which can influence this "two-hit" response. This paper explores how traumatic injury triggers a unique immune response, possibly initiated by damage-associated molecular pattern molecules (DAMPs), a mix of endogenous danger signals, including alarmins and pathogen-associated molecular pattern molecules (PAMPs).

В данной статье описывается разработанный российскими учёными элективный модуль «Развитие личностного потенциала - лайт версия» для будущих педагогов - студентов первого курса в Московском Городском педагогическом Университете (Россия), включающий в себя три дисциплины «Образовательная среда как вектор личностного роста и развития», «Социально-эмоциональный интеллект: как понимать свои и чужие эмоции», «Soft skills 21 века – что такое 4 К?». Автор рекомендует комплексно изучить данный опыт и учитывая особенности педагогической системы Узбекистана использовать его при подготовке будущих педагогов, а так же в переподготовке и повышении квалификации педагогических кадров для повышения их личностного потенциала в целях повышени качества образования в школах.

Ushbu maqolada amnion pardaning muddatidan oldin erta yorilishi sabablari, klinikasi, diagnostikasi, asoratlari va Farg’ona  viloyatida uchrash statistikasi bo’yicha olib borilgan izlanishlarning qisqacha bayoni keltirilgan. Farg’ona viloyat bo’yicha 2023-yil davomida 5892 ta muddatidan oldingi tug’ruq kuzatilgan va bu tug’ruqlarning 30%  APMOEY bilan murojaat qilib kelgan.  Bu homilador ayollarning 4695 tasi 33- 37 hafta va 1015 tasi 28-32 hafta, 182 tasi 22 -27 haftalik homilador bo’lgan. Ular statsionarda davolangan, ularda antibiotikoterapiya, steroidlar bilan davolash, tokolitiklar bilan davolash amaliyotlari o’tkazilgan.

Visual impairment is one of the most common diseases in the world. According to the World Health Organization (WHO), myopia has spread to 1.6 billion people in recent years and is predicted to reach 5 billion by 2050. Carrying out a number of studies in case of dysfunction of a particular organ allows us to determine changes in special topographic areas of the musculoskeletal system against the background of diseases. Craniometry is considered one of the important sections of anthropometry, and the determination of anatomical changes in craniometric parameters is of great importance for theoretical and practical medicine.

The study provides detailed findings from an extensive immunomorphological examination of blood in children with congenital heart defects. It uncovers the distinct patterns of immunodeficiency development that vary based on the specific types of heart defects.

Arterial hypertension (AH), a prevalent chronic condition, is marked by consistently elevated blood pressure. Beyond the primary mechanisms contributing to the development of hypertension—such as activation of the sympathetic nervous system, disturbances in the renin-angiotensin-aldosterone system, endothelial dysfunction, heightened vascular reactivity, and vascular remodeling—inflammation is also thought to play a role in the disease's formation. This review delves into the role of cytokines in the pathogenesis of AH, examining how they interact with the body's blood pressure regulatory systems.

This information was more important than ever in the 1900s. Unfamiliar infectious diseases can be imported into industrialized countries due to population migration and low flight prices. The industrial Revolution in Europe in the 18th century increased the proportion of women in the workforce. This increased further after World War II, which led to an increase in the number of women in the workforce. Their participation in the labor force has influenced the structure of families, so today they are more inclined to the structure of nuclear families than to large families who have assumed responsibility for caring for children whose parents are absent.The outbreak of severe acute respiratory syndrome, first discovered in 2003, is an example of this. Despite modern technology and significant financial investments, it took several months to identify the pathogen, create diagnostic testing, and develop a disease reporting and isolation plan. The control and prevention of infectious diseases depend on understanding the sources of transmission. This article summarizes the basic principles of transmission of infectious diseases, as well as highlights the numerous factors that determine the causative agent, host and environment of these diseases. These factors are of particular importance for medical professionals. In addition, the basic principles of prevention, diagnosis and control of infectious diseases will be considered.

Ushbu maqola surunkali allergik dermatitni davolashda xalq tabobati usullarini optimallashtirishni o'rganadi. Allergik dermatit - bu qichishish, qizarish va terining shikastlanishi bilan tavsiflangan keng tarqalgan yallig'lanishli teri kasalligi. An'anaviy tibbiy muolajalar mavjud bo'lsa-da, ba'zi odamlar o'zlarining alomatlarini boshqarish uchun muqobil yondashuvlarni, jumladan, xalq tabobati usullarini izlaydilar. Ushbu tadqiqot turli xil xalq tabobati usullarining samaradorligi va xavfsizligini o'rganish va surunkali allergik dermatitni davolash uchun ularni optimallashtirish haqida tushuncha berishga qaratilgan. Maqolada dorivor o'simliklar, parhezni o'zgartirish, turmush tarzini o'zgartirish va ong-tana texnikasi kabi bir qator xalq tabobati amaliyotlari ko'rib chiqiladi va ularning potentsial foydalari va cheklovlari baholanadi. Bundan tashqari, u dalillarga asoslangan tibbiyotning ahamiyati, sog'liqni saqlash mutaxassislari bilan hamkorlik va surunkali allergik dermatitni davolashda xalq tabobati usullarining samaradorligi va xavfsizligini tasdiqlash uchun keyingi tadqiqotlar zarurligini muhokama qiladi.

This article is devoted to revealing the importance of heart transplantation using the example of the English experience. The following are various recommendations and warnings for heart transplantation.

Ushbu maqolada plantaskopiya usulining dermatoglifika va tibbiyotdagi amaliy ahamiyati haqida ma’lumotlar berib o’tilgan bo’lib, zamonaviy standart plantaskopiyaning bemorlardagi tashxisi haqida tushunchalar berib o’tilgan.

Parazitologiya kompleks biologik fan bo'lib, parazitlar biologiyasi va ekologiyasi, parazitizm xillari va shuningdek, parazitlar qo'zg'atadigan kasalliklar hamda ularga qarshi kurash usullarini o'rganuvchi  fandir. Odamda uchraydigan parazitlarni, ular keltirib chiqaradigan kasalliklarni va ularga qarshi kurash  usullarini o'rganadigan fan tibbiy parazitologiya deyiladi.

Arteriovenous malformations (AVMs) are developmental anomalies of the vascular system characterized by tangles of poorly formed blood vessels, where feeding arteries are directly connected to a venous drainage network without an interposed capillary system. While AVMs can occur anywhere in the body, brain AVMs are particularly concerning due to the high risk of bleeding, which can cause neurological damage. This article reviews the pathophysiology, clinical presentation, and emphasizes the importance of the interprofessional team's role in managing these patients.

The management of dental caries has undergone significant evolution in recent years. Contemporary practical strategies now emphasize early detection and prevention, along with diagnostic assessments based on risk indicators and factors. The latest management approaches prioritize the preservation of healthy tooth structure, aligning with the principles of minimally invasive dentistry. These approaches aim to fulfill multiple objectives, including fostering a preventive mindset, tailoring risk assessments to individual patients, promptly identifying carious lesions, and promoting remineralization of non-cavitated lesions.

Balg’am ajralishi bu yuqori nafas yo’llari yallig’lanishi natijasida Bronx devorlarida shilliq modda ajralishi bilan kechadigan holat. Shuningdek balg’am ajralishi ko’pgina nafas yo’li kasalliklarining yonaki belgisi ham xisoblanib organizmda himoya funksiyasini ham bajaradi, yani organizmdagi yot moddalarni balg’am orqali chiqarib tashlanishini ta’minlaydi. Lekn doim ham balg’am ajralishgi kutilgandek sodr bo’lmaydi, boshqa so’z bilan tushuntiriladigan bo’lsa, balg’am quyuq va yopishqoq bo’lishi uni Bronx devorlaridan ajralib chiqib ketishini qiyinlashtiradi. Bunday holatlarda balg’amchi suyultiruvchi va yopishqoqligini kamaytiruvchi dori vositalaridan foydalaniladi. Shu o’rinda O’zbekiston Respublikasi Farmatsevtika bozorida mahalliy korxonalar tomonidan ishlab chiqarilgan va horijiy davlatlardan import qilib keltirilgan bal’gam ko’chiruvchi xususiyatga ega bo’lgan dori vositalarining tahlili ushbu maqolada keltiriladi. Tahlil dori vositalarining ta’sir etuvchisining kelib chiqishi, qanday dori shaklida chiqarilganligi, ishlab chiqaruvchi korxonasi va qanday xalqaro nom ostida ishlab chiqarilganligi bo’yicha amalga oshirildi. Tahlil natijalari shuni ko’rsatdiki mahalliy korxonalar tomonidan ishlab chiqariladigan balg’am ko’chiruvchi dori vositalaririning 40% yaqini qiyom shaklida ishlab chiqarilar ekan, shuningdek o’simlik xom ashyosi asosida tayyorlangan dori vositalarining aksariyati gulxayri va shirinmiya o’simligi asosida olinganligi ma’lum bo’ldi. Balg’am ko’chiruvchi dori vositalarining horijdan kewltirilganini esa aksariyati Hindiston davlatidan olib kelinganligi aniqlandi. Hamda O’zbekiston Respublikasi dori vositalari Reesteri asosida 3 yillik ma’lumotlar ustida izlanish olib borilishi natijasida balg’am ko’chiruvchi vositalar eritma ko’rinishida ishlab chiqarish ko’rsatkichi 20% dan 27% ga oshgani aniqlandi.

Моторное растение Allium или луковица мадора-двулетнее растение, принадлежащее к семейству тюльпанов [1]. Хорошо растет преимущественно в предгорьях Чаткальской горной зоны Узбекистана. Растет и собирает урожай (надземная часть) в основном весной, то есть в апреле и мае ^[2]. Моторное растение Allium также можно легко выращивать в теплицах. Поскольку моторное растение Allium является лекарственным растением, его много едят (в основном надземное) [3]. Поскольку растение богато витаминами, белками и углеводами [5], его также можно использовать для улучшения иммунной системы [4].Полученные экстракты анализировали на флавоноиды с помощью ВЭЖХ.

The article presents literature data on the frequency, main clinical manifestations, modern methods of early neonatal and postnatal diagnosis, treatment and prognosis of tetrad Fallot is a congenital defect of the cardiovascular system.

Ushbu tadqiqot sanoat korxonalari va fabrikalar tomonidan chiqariladigan zararli mahsulotlarning inson salomatligiga salbiy ta'sirini o'rganadi. Bu muassasalar tomonidan atrof-muhitga chiqariladigan turli ifloslantiruvchi moddalar va ularning odamlar farovonligiga ta'siri o'rganiladi. Har tomonlama tahlil qilish va ma'lumotlarni to'plash orqali tadqiqot sanoat ifloslanishi bilan bog'liq sog'liq uchun xavflar haqida xabardorlikni oshirish va uning inson salomatligiga salbiy ta'sirini yumshatish choralarini qo'llab-quvvatlashga qaratilgan.

This article examines the hygienic features of greenhouse vegetable production using restricted soil in Uzbekistan. With the increasing demand for high-quality vegetables, greenhouse production has become a vital part of Uzbekistan’s agricultural strategy. However, the unique climatic and soil conditions in the region pose specific challenges related to hygiene and food safety. This study investigates the sanitary practices, soil management techniques, and environmental controls employed in Uzbek greenhouses to ensure the production of safe and healthy vegetables. Through a combination of field observations, laboratory analyses, and surveys of local agricultural practices, the research identifies key hygienic practices that mitigate contamination risks. The findings highlight the importance of rigorous hygiene protocols and soil management strategies in maintaining the quality and safety of greenhouse-grown vegetables. Recommendations for improving current practices and policy implications are also discussed to enhance the sustainability and safety of greenhouse vegetable production in Uzbekistan.

Мақолада эксперементал токсик гепатитда ядро аппарати реакциясининг хусусиятлари ўрганиб чиқилган. Жигарнинг ядро аппаратини ўрганиш билан боғлиқ бир нечта тажрибаларни ўтказганимиздан сўнг, биз олдимизга янги вазифа қўйдик - жигар патологиясида, яъни репаратив регенерациясида ядрочанинг ролини аниқлаш. Оқ каламушлар жигари нормал ва патологик шароитда ўрганиб чиқилган. Жигар токсик гепатити моделлаштирилган хайвонларнинг гепатоцитлари, ядролари ва цитоплазмасининг холатини тўлиқ тахлил қилиш шуни кўрсатдики, гепатоцит ядросидан ядроча донадор компоненти цитоплазмага чиқиши жигар патологиясида хам учрар экан.

В данной статье описываются особенности клинического течения и клинико-биохимических лабораторных изменений у 21 пациентки легкой степени тяжести рецидивирующей формы внутрипеченочного холестаза у беременных из 112 страдающих внутрипеченочным холестазом беременных.

Мақолага Қорақалпоғистонннинг кам шўрланган тупроқлари шароитида нўхат навларининг ўсиб-ривожланишига экиш муддатларининг таъсирини ўрганиш юзасидан олинган маълумотлар киритилган. Тадқиқотлар апрел ойининг I, II, III декадаларида экилган «Палвон», «Суплик» ва «Юлдуз» навларида ўтказилиб, тадқиқот натижаларига кўра апрел ойи I-ўн кунлигида экилган «Суплик» нави бошқа навларга нисбатан юқори кўрсаткичларга эгалиги ҳамда мазкур муддат «Суплик» нави учун мақбул эканлиги келтирилган.

Olinadigan protezlar mahkamlash tizimidan foydalanishni talab qiladi va ko‘pincha stomatologlar o‘z ishlarida klammerlardan (oddiy ilgaklar) foydalanadilar. Ular mahsulotni bir vaqtning o‘zida bir yoki bir nechta tishlarga tuzatish kerak bo‘lganda qo‘llaniladi. Ko‘rinib turgan soddaligiga qaramay, ularning individual xususiyatlari, afzalliklari va kamchiliklari bilan bir nechta turlari mavjud.

Climate change has become an important global problem affecting various aspects of human health. Among the health problems involved, vascular diseases are gaining increasing attention due to their prevalence and severity. This article examines the impact of climate change on patients with vascular diseases, including cardiovascular disease, peripheral arterial disease, and cerebrovascular disease. Explores how changing environmental factors, such as temperature, air pollution, and extreme weather events, can exacerbate vascular disease, increase disease burden, and impact patient outcomes. In addition, potential adaptive strategies and measures to mitigate the adverse effects of climate change on vascular health are discussed.