AKSIAL SPONDILOARTRITNING PROGRESSIV KECHISHIDA ZARDOBDAGI ANNEXIN A1 DARAJASINING KLINIK AHAMIYATI

Article Sidebar

PDF (Русский)
Issue: Vol. 3 No. 60 : Science and Innovation
Section: Articles
Published:

Main Article Content

Toshkent davlat tibbiyot universiteti
info@in-academy.uz
Toshkent davlat tibbiyot universiteti
info@in-academy.uz
Toshkent davlat tibbiyot universiteti
info@in-academy.uz

Abstract:

Aksial spondiloartrit (AksSpA) umurtqa pog‘onasi va sakroiliak bo‘g‘imlarning surunkali yallig‘lanishi bilan kechib, asosan mehnatga layoqatli yosh aholi orasida uchraydi va erta nogironlikka olib kelishi bilan ahamiyatlidir. Kasallikning dastlabki, norrentgenologik bosqichlarida strukturaviy o‘zgarishlarning aniq ko‘rinmasligi erta tashxis qo‘yishni qiyinlashtiradi. Shu bois kasallikni erta aniqlash va kechishini prognozlash imkonini beruvchi biomarkerlarni izlash dolzarb muammo hisoblanadi. Annexin A1 (ANXA1) yallig‘lanishga qarshi va immunoregulyator xususiyatlarga ega bo‘lib, uning AksSpAdagi klinik ahamiyati yetarlicha o‘rganilmagan.

Article Details

How to Cite:

Ikramova, D., Eshmurzaeva, A., & Karimov, M. (2025). AKSIAL SPONDILOARTRITNING PROGRESSIV KECHISHIDA ZARDOBDAGI ANNEXIN A1 DARAJASINING KLINIK AHAMIYATI. Science and Innovation, 3(60), 146–147. Retrieved from https://in-academy.uz/index.php/si/article/view/70116

References:

Braun J., Sieper J. Axial spondyloarthritis. Lancet. 2007;369(9570):1379–1390.

Sieper J., Poddubnyy D. Axial spondyloarthritis. Lancet. 2017;390(10089):73–84.

van der Heijde D. et al. Assessment of radiographic progression in ankylosing spondylitis. Arthritis Rheum. 2004;50(8):2622–2632.

Perretti M., D’Acquisto F. Annexin A1 and glucocorticoids as effectors of the resolution of inflammation. Nat Rev Immunol. 2009;9(1):62–70.

Yang Y.H., Morand E.F. Annexin A1 and glucocorticoid receptors in inflammatory diseases. Trends Immunol. 2010;31(9):337–343.

Poddubnyy D., Rudwaleit M. Early diagnosis of axial spondyloarthritis. Ann Rheum Dis. 2013;72(7):1061–1067.