The share of frequently ill children on average accounts for up to 70-85% of all cases of respiratory diseases in children (1,5,6).  Recent studies have shown that bronchopulmonary diseases often develop against the background of a violation of the normal functioning of the immune system, and in some cases of immunodeficiency states - primary and secondary. Consequently, immunotherapy plays an important role in the therapeutic tactics of obstructive bronchitis (2,3,7).