Ushbu ilmiy maqolada folat kislotasining (vitamin B9) biokimyoviy va fiziologik funksiyalari, uning hujayra bo‘linishi, DNK va RNK sintezi, metilatsiya jarayonlari, gemopoez hamda embrional rivojlanishdagi ahamiyati chuqur tahlil qilindi. Folat yetishmovchiligining patofiziologik mexanizmlari, global va mintaqaviy epidemiologik ko‘rsatkichlar, klinik oqibatlar — megaloblastik anemiya, homilaning neytral naycha nuqsonlari, yurak-qon tomir kasalliklari, depressiya va kognitiv buzilishlar ilmiy dalillar asosida yoritildi. Xavf guruhlari, homiladorlik paytidagi folat ehtiyoji, mikronutrientlar yetishmovchiligi bilan bog‘liq xavflar va fortifikatsiya dasturlarining samaradorligi baholandi. Tadqiqot natijalari folat kislotasining yetarli darajada iste’moli perinatal sog‘liq, neonatal nogironlikning oldini olish, gematologik va kardiometabolik kasalliklar xavfini kamaytirishda muhim omil ekanini tasdiqlaydi.

Elevated serum homocysteine levels (hyperhomocysteinemia) represent a significant risk factor for fetal developmental disorders during pregnancy. High concentrations of homocysteine exert a toxic effect on the vascular endothelium, lead to impaired placental circulation, increase the risk of thrombophilic complications, and can cause neural tube defects, intrauterine growth restriction, preeclampsia, and even pregnancy loss. This article discusses the pathogenetic mechanisms of hyperhomocysteinemia's effect on embryogenesis, the clinical consequences for the fetus, and current methods for diagnosing and correcting this condition, including the use of folic acid, B vitamins, and anticoagulant therapy, with an emphasis on data from the last five years.

The paper presents the results of a study of the vitamin composition of a dry extract obtained on the basis of various solvents (80% ethanol, butanol) from the leaves of medicinal sage - Salvia officinalis L., cultivated in Uzbekistan. The samples were found to contain vitamins С, В₁, В₂, В₃, В₆, В₉, which play an important role in the body. Among them, the most quantitatively dominant are riboflavin (B₂) and folic acid (B₉), the deficiency of which can cause a deterioration in the general condition of the body, depression, deterioration of the nervous system, as well as dry skin, burning eyes and photosensitivity, anemia, fatigue and irritability. The obtained data will be in demand for the chemical characterization of dry extracts and their subsequent standardization.

This article contains detailed information about the types of pumpkin plant, its chemical composition and medicinal properties, and diseases of pumpkin plant.

Before we get into the healing properties that this food gives us, let's first tell you what it contains, because it is its components that make our body healthy. It has a lot of amino acids. How oleic, silicic or palmitic acid, It provides us with vitamin C, which is a B group of vitamins. On the other hand, the work of vitamin E or folic acid stands out.

Citrus fruits are vitamin C, potassium, folic acid, bioflavonoids, fiber, essential oils - “solid vitamins”. Citrus fruits got their name from the lemon, which in Latin is called citrus. In addition to the lemon, there are many other edible citrus fruits - and almost all of them are bred by humans from a dozen wild species.