This article analyzes the clinical features of the course and electrocardiographic (ECG) changes in coronary heart disease (CHD) in men at a young and old age. The study included 230 patients with coronary artery disease. All patients depending on age were divided into 2 groups: the 1st group included 126 young patients, the 2nd group included 104 elderly patients. The main diagnostic methods were patient interviews, ECG, Holter monitoring. According to the results of the study, it was found that the occurrence of anginal attacks from 6 to 8 times during the day was observed in 85 (67.5%) patients of the 1st group, in 82 (78.8%) patients in the 2nd group, which indicated about the severity of the disease