Further methods have been combined with culture to successfully diagnose TB including, the chest X-ray and the Tuberculin skin test . Received the results confirm high sensitivity (in all patients with local forms of tuberculosis DST was positive) and the specificity of DST (in all children with post-vaccination allergic a negative reaction to DST was noted), which allows it to be used for differentiation al diagnostics of post-vaccination and infectious allergy in children. The highest frequency of positive of TB risk groups was observed in the contact group (50.6%). Significantly a large number of cases (13 out of 26), contact with patients with bacterial excretion was detected only retrospectively, after the detection of TB disease (1/2 of them had contact with patients excreting among MBT strains with multidrug resistance, 2/3 had familial tuberculosistact). It is necessary to improve the work on identifying contacts and their examination, expanding the sanatorium-type institutions for separation and isolation of children from foci of tuberculosis.