This article provides a broad analysis of the historical development of humanistic ideas in Uzbek literature. Starting from ancient written monuments, it examines the various manifestations of humanism during the Eastern Renaissance, the Timurid literary school, the Jadid movement, and contemporary literature of the independence period. Through the works of such writers as Alisher Navoi, Zahiriddin Muhammad Babur, Abdulla Qodiriy, Cho‘lpon, Erkin Vohidov, Abdulla Oripov, and Tog‘ay Murod, the concepts of human dignity, justice, compassion, freedom, and spiritual perfection are highlighted. Furthermore, the views of scholars are presented, enriched with literary criticism perspectives. The results of the study demonstrate that humanism is inherent to all stages of Uzbek literature, serving as an important spiritual foundation that unites national and universal values.