The widespread adoption of e-learning systems has significantly increased the volume of data related to student activity, including login behavior, content interaction, and learning engagement patterns. While such data provide valuable insights into learning processes, many PHP-based e-learning systems lack intelligent monitoring mechanisms capable of analyzing student activity in real time. As a result, academic supervision often relies on manual observation or static activity reports, which limits the effectiveness of timely interventions. This article investigates the design and implementation of intelligent monitoring mechanisms for student activity in PHP-based e-learning systems. The proposed approach integrates artificial intelligence techniques into a traditional PHP platform to enable automated tracking, analysis, and interpretation of student activity data. By leveraging AI-driven monitoring, the system aims to identify abnormal behavior patterns, detect disengagement, and support proactive academic supervision. The results demonstrate that intelligent monitoring enhances the visibility of student activity dynamics and enables early identification of potential learning risks. The proposed framework shows that artificial intelligence can be effectively integrated into PHP-based e-learning environments to support continuous monitoring without requiring extensive system restructuring. This research contributes to the development of intelligent e-learning systems by providing a practical model for AI-supported student activity monitoring in widely used web-based platforms.

The effect of different concentrations of fat and fat hydrolysis products on the proteolytic activity of the pancreas and gastric juice was studied using casein-fat emulsion (casein+tributrin, casein+sunflower oil). Under the influence of sunflower oil hydrolysis products, the total proteolytic activity of pancreatic juice clearly decreased, but this indicator did not change under the influence of tributyrin hydrolysis products. Hydrolysis products of sunflower oil and tributyrin oil do not affect the total proteolytic activity in gastric acid environment. We saw a decrease in the proteolytic activity of the pancreas when the concentration of the above-mentioned fats was increased in the composition of the casein + fat emulsion. Increasing the concentration of fats affects the proteolytic activity of gastric juice.

The article emphasizes the scientific orientation of increasing the social activity of women in Uzbekistan at the level of state policy and strategy. Also, socialization is a controlled and purposeful process of self-transformation and development throughout a person's life, socialization of women is a social environment that surrounds women, family, state and society, the media, education and science, work and activity. has been scientifically analyzed for widespread use in sports and culture, art and literature. In particular, activation is a distinctive feature, a dynamic activity, which means the ability to independently organize your time. The activity is characterized by purposefulness, motivation, initiative. Activity is also the ability to satisfy the needs of your soul, to be fully interested in life.

This article presents the results of a study of the psychopharmacological activity of BAC, obtained on the basis of vegetation common in our country. The studied substance was studied by the action and search, the anxiolytic activity of experimental animals, as well as by oral administration at doses of 5.0 and 15 mg/kg of its activity in relation to emotions or fear. As a result of the screening studies, it was noticed that the action and search activity of experimental animals decreased under the influence of the substance under study. At the same time, this substance showed little anxiolytic activity in relation to the control group. Also, in the Sonberg method, the excretion of urine and excrement by experimental animals decreased due to noise and external factors. Thus, based on the conducted screening study, it can be concluded that the studied substances significantly reduce fear and emotional arousal. This indicates that the studied substances have a calming effect.

Adaptation to professional activity is the process of a person entering a profession, expressed in its goals, content, technologies, means of implementation, order and intensity of activity, production and labor discipline, organizational rules and norms, and flexibility to other requirements. It is believed that external assistance from professional psychologists, including instructors, reduces the difficulties of adaptation and contributes to success in overcoming difficulties in ensuring adaptation to the social conditions in which a specialist's professional activity takes place. In this sense, the peculiarities of adaptation to professional activity have been analyzed.

Lectin was extracted from Phaseolus vulgaris seeds and purified using Affi-gel blue gel, fast protein liquid chromatography (FPLC) – ion-exchange chromatography, and FPLC-gel filtration methods. The lectin consists of two 30 kDa subunits, and its N-terminal structure was found to be similar to other Phaseolus lectins. The hemagglutination activity of the lectin remained stable within a pH range of 1-14 and a temperature range of 0-80°C. The lectin strongly inhibited the proliferation of MCF-7 (breast cancer) cells with an IC50 of 1.3 μM and suppressed HIV-1 reverse transcriptase activity with an IC50 of 7.6 μM. The lectin also exhibited activity by increasing [3H-methyl]-thymidine incorporation in mouse splenocytes in response to a mitogenic stimulus. However, it did not stimulate nitric oxide production in murine peritoneal macrophages. Chemical modification results indicated that tryptophan is crucial for the hemagglutination activity of the lectin.

Development of cognitive activity of students of primary school age is one of the urgent problems in modern education. This article describes the tasks of the school psychologist in the development of the knowledge of primary school students, the formation of cognitive educational activity in increasing the effectiveness of education and its stimulation, and the theoretical basis of the technology of cognitive activity.

The recognition of language's fundamental role in cognitive activity has led to the fact that the subject of cognition has become the subject of study not only for philosophy, psychology, and logic but also for linguistics. At the present stage of scientific development, this anthropocentric coordinate is considered as the leading role characteristic of human manifestation in language. This was based on numerous studies that significantly broadened the perspective on the problem of language anthropocentrism, proving that it is not confined within the framework of speech activity and is closely connected with mental activity.

The article analyzes data on the general, seasonal and sexual activity of the terrestrial mollusk Xeropicta candaharica. As a result of studying the activity of this species of mollusk in natural and laboratory conditions, the following was determined. The general activity of X. candaharica mollusks in the spring period was observed at air temperatures from +5^oC to +23^oC and relative humidity from 45% to 100%, sexual activity was observed at air temperatures from +5^oC to +19^oC, relative humidity from 55% to 95%, and the egg-laying process was observed at air temperatures from +1^oC to +21^oC, relative humidity from 63% to 90%. The development period of eggs in the natural environment lasted 11-16 days and depended on air temperature. At an average daily air temperature of +12^oC, the eggs developed for 15-16 days, and at +14^oC for 11-13 days. In laboratory conditions, at an average daily air temperature of +15.5^oC, the eggs developed for 18-20 days.

"Physiology of cardiac activity" discusses the intricate workings of the heart and the physiological processes involved in regulating its activity. The annotation provides a comprehensive overview of the topic, including the structure and function of the heart, the cardiac cycle, and the electrical conduction system. Additionally, it explores the regulation of cardiac activity through the autonomic nervous system and hormonal control. The annotation may also touch upon common cardiac disorders and the importance of understanding the physiology behind cardiac activity for medical professionals and researchers in the field of cardiology. This topic is essential for anyone interested in gaining a deeper understanding of the mechanisms that drive the pumping action of the heart and its role in maintaining overall body function.

This article provides a scientific analysis of the medicinal properties of essential oil obtained from peppermint (Mentha piperita), with particular emphasis on its antibacterial and antifungal activities. Peppermint essential oil has long been used in traditional medicine for the prevention and treatment of various infectious diseases. The study investigated the chemical composition of peppermint essential oil and the effects of its main bioactive components—menthol, menthone, and other terpenoids—on microorganisms. Antibacterial activity was evaluated using the disk diffusion method, while antifungal activity was assessed based on minimal inhibitory concentration (MIC) values. The results demonstrated that peppermint essential oil exhibits significant inhibitory effects against pathogenic bacteria and fungi. These findings provide a scientific basis for the medicinal properties of peppermint essential oil and expand the possibilities for its application as a natural antimicrobial agent in medicine and pharmaceutical industries.

This article analyzes the content of the formation of children's independent musical activity, its main directions and the role of pedagogical leadership from a scientific and theoretical perspective. Independent musical activity is considered an important factor in the development of children's aesthetic taste, creative potential, musical hearing and rhythmic perception. The article covers the formation of the child's musical perception through the processes of singing, listening, dancing, playing musical instruments and improvisation. Also, the educator's leadership activity in the process of musical education is explained on the basis of encouraging the child's independence, creating a positive environment and ensuring an individual approach. The results of the study show that organizing musical education on the basis of modern technologies has an effective impact on the emotional, intellectual and creative development of children.

The article examines creative pedagogical activity as a heuristic component of personality development, the stages of its formation, criteria for pedagogical creativity, spheres of creative activity of a teacher, self-education and self-realization of a teacher.

Connective tissue dysplasia (CTD) is a group of hereditary diseases characterized by disruption of the structure and function of connective tissue, which can affect various organs and systems, including the cardiovascular system. One of the main molecular mechanisms contributing to the development of pathologies in CTD is an imbalance in the activity of matrix metalloproteinases (MMPs), which are responsible for the destruction of the extracellular matrix. The purpose of this study is to assess the activity of MMP in plasma in a child with connective tissue dysplasia of the heart and to analyze the role of the gelatin zymography method in the study of myocardial remodeling. The paper presents a clinical case of a 13-year-old girl with cardiac connective tissue dysplasia. To assess MMP activity, the gelatin zymography method was used, which revealed a significant increase in the activity of MMP-2 and MMP-9, which indicates pathological processes of degradation of the extracellular matrix and impaired myocardial remodeling. The results obtained confirm the importance of this method in the diagnosis of diseases associated with cardiac remodeling and highlight its potential in clinical practice for monitoring the progression of diseases associated with connective tissue disorders.

Article deals with the methods of developing of cognitive activity of cadets in the process of teaching English. There was indicated the importance of developing of cognitive of cadets  and worked out the  exercises directed to the developing of cognitive activity. Given educational games  can serve for developing of cognitive activity of cadets. 

This article examines the role of visual activity in the upbringing of children and its significance in aesthetic education. Visual activity is an important tool not only for the development of children's aesthetic feelings, but also for the development of creative thinking, emotional expression, and cognitive skills. The article analyzes methods for effectively organizing visual activity through pedagogical methods and approaches (visual, creative, practical work), their role in enhancing children's aesthetic feelings and creative abilities. Through aesthetic education, children learn to understand beauty, manage their emotions, and develop social skills. This article explains the pedagogical significance of visual activity and its role in the upbringing of children.

In the work, monochloromethane was selected for heating (at high temperature) in an air- absorbed environment. Methods of selecting a binding component for a catalyst that has a low catalytic activity and retains the characteristic of selective action are shown . Experiments were carried out in a catalyst bed reactor at temperatures of 400-500℃ and a volumetric rate of monochloromethane of 450-2000 h^-1. In the process Mg-P-Zr-Fe/YukS-20; Mg-P-Zr-Fe/YukS-30 catalysts were used. In the Mg-P-Zr-Fe/YukS-20 sample, the conversion of monochloromethane was 66%, after 500 min, up to 42% of the monochloromethane conversion in Mg-P-Zr-Fe/YukS-20, Mg-P-Zr And in Fe/YukS-30 it decreased to 36%. Al ₂ O ₃ was recommended to be used as a binder component, but the introduction of a binder led to a decrease in activity. The acidic properties of ammonia were studied using the method of thermoprogrammed desorption of ammonia. The regeneration process of the deactivated catalyst in the pyrolysis of monochloromethane was carried out using the method of combustion in air flow. Unreacted monochloromethane and reaction products were determined by the GSX method. In addition, the total selectivity of ∑C ₂ -C ₃ in Mg-P-Zr-Fe/YukS-30 is 6.75 mol% higher than in Mg-P-Zr-Fe/YukS-20, and both Mg-P-Zr-Fe/ The activity of YuKS-20 and Mg-P-Zr-Fe/YukS-30 catalysts decreases to 36.8% and 36.6% after 500 min of operation, which indicates the similarity in their deactivation. The purpose of the work is to create a bond for a slightly higher catalytically active and selective catalyst, which is separately isolated for the heating process of monochloromethane in an air-absorbed, i.e., vacuum environment, by slowly increasing the temperature. consists in choosing the constituent component.

This article discusses the goals and objectives of problem-based learning, which is one of the most effective teaching technologies in the current education system, the role and importance of the teacher, and at the same time the development of the student's ability to think independently, critically and creatively, the creative mastery of knowledge, skills and competencies as a result of active independent activity, and the development of mental activity.

In this article, the acute toxicological properties and local analgesic (anesthetic) activity of tannins isolated from plants Salvia Sclarea L. (sage) and Matricaria Chamomilla L. (chamomile) were studied on an experimental animal model (mice). The acute toxicity index was studied by oral administration (per os) of the substance to animals in various doses (100.0–15800.0 mg/kg). The experimental results showed that the acute toxicity index, estimated by LD₅₀, was 14600.3 mg/kg with oral administration of tannin, which confirms the classification of this substance as low-toxic. The anesthetic activity was studied using the methods of Rainier, as well as Bulbring and Vida. In experiments conducted using the Rainier method with 0.5% tannin solution, the time of onset of anesthesia was 3.7±0.3 minutes, the time of complete anesthesia was 12.1±0.7 minutes, and the total duration was 15.8 ± 0.9 minutes. The results of the Bulbring and Vida method confirmed that the substance has a dose-dependent pain-reducing effect; in this model, the maximum effect of 0.5% tannin solution was also observed. The results of the study show the prospects of introducing tannins of natural origin into medical practice as a low-toxic compound with local analgesic effect.

The aim of the study was to investigate the effect of the drug "Reomannisol" in patients with injuries of different etiology on the activity of lipid peroxidation (LPO) and the state of antioxidant system (AOS). The study was conducted in the surgical intensive care unit of the Republican Specialized Scientific and Practical Medical Center of Traumatology and Orthopedics (RSSPMCTO). The obtained data show that the investigated preparation has a pronounced antioxidant effect, increases the activity of AOS enzymes, thus stabilizing biomembranes. Application of the preparation "Reomannisol" effectively restored hemodynamic physiological and blood biochemical analysis indices in clinical application in patients with various types of musculoskeletal traumas, in hemorrhagic shock, as well as effectively reduced the intensity of lipid peroxidation processes, increased the activity of antioxidant defense enzymes and by its activity is not inferior to the preparation "Rheosorbilact".

Aromatase is a key enzyme in the conversion of androgens to estrogens in the ovaries and other tissues and organs. To study the role of aromatase in the pathogenesis of external genital endometriosis (NGE) 57 patients with NGE were examined and 15 healthy women of reproductive age. Aromatase activity was determined by the reaction of estrogens to the aromatase inhibitor letrozole. The ovarian source of the determined aromatase activity was determined by the suppression of the reaction to letrozole against the background of the use of the gonadotropin releasing hormone agonist. Aromatic activity in terms of antral. The follicle in patients with grade II–IV NE was higher than in healthy women, however, the total aromatic activity of the ovaries due to the low number of antral follicles did not differ from the indicator in the control group. Violation of folliculogenesis in NGE is probably associated with the revealed hyperestrogenemia of ovarian and extra-gonadal origin.

The early years of a child's life are critical for physical, cognitive, and social development. Motor activity forms the foundation for a child’s overall health and learning readiness. This article explores the significance of play-based methods in stimulating and developing motor activity in preschool-aged children. Through a combination of observational analysis and literature review, the study emphasizes how structured and unstructured physical games promote motor skills and contribute to holistic development.

From the aerial part of the plant Onobrychis grandis Lipsky (Fabaceae) growing in the territory of Uzbekistan, the phenolic glycoside arbutin was isolated. The parameters of the acute toxicity of arbutin were determined, its analgesic activity was studied in the tests “hot plate,” “acetic writhing” and “acetylcholine writhing.” It was shown that arbutin belongs to low-hazard substances (Class IV according to GOST 12.1.007-76) and practically non-toxic compounds (Class VI according to the classification of A.V. Stefanov). The compound showed pronounced analgesic activity in thermal and chemical (acetic acid) irritation, but did not show a significant effect in the acetylcholine writhing test.

The article examines the role of creative independent tasks in teaching Russian to students of higher educational institutions. Students, independent activity is understood as a type of cognitive activity in which a certain level of independence is assumed in all structural components of the activity for its implementation, from setting a problem to exercising control, self-control and correction with a dialectical transition from performing simple types of work.

This thesis is devoted to the public participation in the process of legislative activity, in which the documents adopted in this area are analyzed. Moreover, theoretical and practical aspects of public participation in legislative activity in Uzbekistan was described.